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Chemerin promoted autophagy by inhibiting the PI3K/Akt/mTOR signaling pathway. (a) The effects of (a) Torin1 and (b) bafilomycin A1 on chemerin-induced autophagy were detected by western blot. (c) The effects of Torin1 and bafilomycin A1 on (c) chemerin-induced proliferation and (d) chemerin-induced apoptosis. Bars show mean ± standard deviation of three independent experiments. **P < 0.01 vs. LV5-control, #P < 0.05, ###P < 0.001 vs. LV5-chemerin.
