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. 2021 Dec 1;14:6397–6407. doi: 10.2147/JIR.S339133

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© 2021 Sun et al.

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The overexpression of circFoxo3 represses MI-induced autophagy and inflammation in rat model. (A–H) The MI Rat model was established and treated with injection of circFoxo3 vectors or control vectors surrounding the infarcted region. (A) The levels of LC3 were measured by immunofluorescence. (B–D) The expression of Beclin-1, p62, and LC3 was detected by Western blot analysis. (E–H) The levels of IL-6 and IL-10 were analyzed by ELISA in heart tissues and serum. **p < 0.01.