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. Author manuscript; available in PMC: 2022 Feb 5.
Published in final edited form as: Prim Care Companion CNS Disord. 2021 Aug 5;23(4):21br02930. doi: 10.4088/PCC.21br02930

Table 1 –

Prevalence of Kratom Use and Co-Occurring Substance Use Disorders in the United States, 2019

Never Used Kratom, n=55188 Lifetime Kratom Use, n=948 Prevalence Ratio
(Kratom / Never
Kratom)
Frequency Weighted
Prevalence
(%)
95% CI Frequency Weighted
Prevalence
(%)
95% CI 95% CI
Sex (Female) 26231 51.7 51.0 52.3 557 38.8 34.4 43.4 1.3 1.5 1.2
Age (Years)
12 to 17 13339 10.9 10.6 11.2 58 4.0 2.9 5.4 0.4 0.3 0.5
18 to 25 13844 7.4 7.2 7.6 382 13.6 11.3 16.2 1.8 1.5 2.2
26 to 34 8342 17.4 16.9 18.0 259 37.7 33.2 42.3 2.2 1.9 2.5
35 and Older 19663 64.3 63.7 65.0 249 44.8 39.6 50.1 0.7 0.6 0.8
Race
White 31368 61.7 60.7 62.7 721 81.9 78.1 85.1 1.3 1.3 1.4
Black 7210 12.2 11.4 13.0 46 4.4 2.8 6.6 0.4 0.2 0.6
Hispanic 10749 17.4 16.6 18.2 99 7.6 5.4 10.6 0.4 0.3 0.6
Asian 2686 5.9 5.4 6.4 11 0.9 0.4 2.0 0.2 0.1 0.3
Native American 1022 1.0 0.8 1.1 22 1.2 0.6 2.4 1.3 0.7 2.4
Multirace 2153 1.9 1.8 2.1 49 4.0 2.3 7.0 2.1 1.2 3.6
Past Year Major Depressive Episode 4228 7.6 7.2 8.0 239 26.7 22.7 31.0 3.5 3.0 4.1
Past Year Substance Abuse or Dependence
Opioids (Heroin or Pain Reliever) 292 0.5 0.4 0.6 77 8.9 6.3 12.5 18.0 12.1 26.9
Heroin only 57 0.1 0.1 0.1 12 0.8 0.3 2.1
Pain Reliever only 214 0.4 0.3 0.5 48 6.2 4.0 9.4
Heroin and Pain Reliever 21 0.04 0.02 0.1 17 2.0 1.2 3.3
Prescription Stimulants 131 0.2 0.1 0.2 26 2.8 1.6 4.6 16.5 9.2 29.5
Methamphetamine 197 0.3 0.3 0.5 44 4.3 2.9 6.5 12.5 8.3 18.8
Cocaine 180 0.3 0.2 0.4 42 4.0 2.6 6.0 14.0 8.5 23.1
Alcohol 3170 5.1 4.8 5.4 193 17.8 14.8 21.3 3.5 2.9 4.2
Marijuana 1474 1.6 1.5 1.8 130 10.6 7.8 14.2 6.6 4.8 9.0
Tranquilizer and/or Sedative 142 0.2 0.2 0.3 32 3.6 2.2 6.1 16.8 9.3 30.6
Hallucinogens 79 0.1 0.1 0.1 11 1.4 0.7 2.8 16.8 9.0 31.1
Any Substance Use Disorder (SUD) 3698 5.9 5.6 6.3 301 31.0 26.6 35.7
1 SUD 3327 5.4 5.1 5.7 224 23.7 20.1 27.8
2 SUDs 278 0.4 0.4 0.5 48 4.5 2.9 6.9
3 or more SUDs 93 0.2 0.1 0.2 29 2.8 1.7 4.6
1

Including opioids, prescription stimulants, methamphetamine, alcohol, marijuana, prescription tranquilizers or sedatives, hallucinogens, cocaine