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Evaluation of two PZA susceptibility testing methods using mixtures of the original susceptible strain 9719 with its PZA-resistant mutant
| % Resistant bacteria in mixture | % Resistant bacteria on agar plates with PZA concn (μg/ml) of:
|
MIC (μg/ml)
|
|||
|---|---|---|---|---|---|
| 300 | 900 | 1,200 | Agar | BACTEC | |
| 0 | 0 | 0 | 0 | <300 | <100 |
| 10 | 13.8 | 8.6 | 8.6 | 900 | >900 |
| 25 | 18.1 | 16.2 | 16.5 | >1,200 | >900 |
| 50 | 35.9 | 36.9 | 40.0 | >1,200 | >900 |
| 100 | 97.8 | 96.1 | 86.2 | >1,200 | >900 |
