Table 5.
Statistical differences between nDKD and DKD subgroups vs control group
| Retinal layers | Controls | nDKD (n = 128 eyes of 64 subjects) | DKD (n = 130 eyes of 65 subjects) | ||||
|---|---|---|---|---|---|---|---|
| MD (µm) ± SD | MD (µm) ± SD | 95% IC | p value | MD (µm) ± SD | 95% IC | p value | |
| Retina | |||||||
| Center (CRT) | 252.0 ± 4.4 | 239.1 ± 3.3 | − 25.9 to 0.3 | 0.059 | 237.1 ± 3.3 | − 28.7 to − 0.9 | 0.032 |
| Total Volume | 8.1 ± 0.1 | 7.8 ± 0.1 | − 0.5 to − 0.1 | 0.005 | 7.9 ± 0.06 | − 0.4 to − 0.02 | 0.025 |
| Inner Temporal | 308.3 ± 3.5 | 298.5 ± 2.3 | − 19.7 to 0.3 | 0.061 | 297.5 ± 2.6 | − 20.7 to − 0.7 | 0.032 |
| Inner Superior | 321.8 ± 3.1 | 309.6 ± 2.4 | − 21.6 to − 2.7 | 0.006 | 310.1 ± 2.6 | − 21.0 to − 2.3 | 0.008 |
| Inner Nasal | 322.2 ± 2.8 | 309.9 ± 2.5 | − 21.3 to − 3.2 | 0.003 | 308.3 ± 3.0 | − 23.1 to − 4.6 | 0.001 |
| Inner Inferior | 320.0 ± 2.6 | 307.8 ± 2.3 | − 20.3 to − 4.1 | 0.001 | 306.6 ± 2.6 | − 21.9 to − 4.9 | 0.001 |
| GCL + | |||||||
| Total | 74.1 ± 1.0 | 70.7 ± 0.7 | − 6.3 to − 0.5 | 0.015 | 70.0 ± 0.9 | − 7.2 to − 0.9 | 0.006 |
| Sup. Temporal | 74.3 ± 1.5 | 70.5 ± 0.8 | − 7.9 to 0.2 | 0.072 | 70.3 ± 0.9 | − 8.2 to 0.2 | 0.065 |
| Superior | 73.6 ± 1.1 | 69.6 ± 0.7 | − 7.1 to − 0.8 | 0.008 | 69.6 ± 0.8 | − 7.3 to − 0.6 | 0.014 |
| Sup. Nasal | 76.9 ± 1.0 | 73.4 ± 0.8 | − 6.4 to 1.0 | 0.019 | 73.3 ± 0.9 | − 6.8 to − 0.3 | 0.024 |
| Inf. Nasal | 75.3 ± 1.0 | 71.8 ± 0.8 | − 6.5 to − 0.4 | 0.018 | 70.8 ± 1.0 | − 8.0 to − 1.0 | 0.006 |
| Inferior | 69.9 ± 1.1 | 67.1 ± 0.7 | − 5.8 to 0.3 | 0.096 | 66.0 ± 1.0 | − 7.3to − 0.4 | 0.022 |
| Inf. Temporal | 74.8 ± 1.1 | 71.8 ± 0.7 | − 6.2 to 0.31 | 0.090 | 70.0 ± 1.0 | − 8.4 to − 1.1 | 0.005 |
| RNFL | |||||||
| Total | 110.5 ± 1.3 | 106.8 ± 1.3 | − 8.2 to 0.7 | 0.131 | 103.9 ± 1.5 | − 11.3 to − 1.8 | 0.003 |
| Temporal | 79.5 ± 1.5 | 76.0 ± 1.3 | − 8.2 to 1.1 | 0.211 | 73.0 ± 1.4 | − 11.7 to − 1.3 | 0.009 |
| Sup. Temporal | 146.8 ± 2.8 | 139.6 ± 2.4 | − 15.9 to 1.5 | 0.148 | 133.3 ± 2.7 | − 22.8 to − 4.1 | 0.002 |
| Inf. Temporal | 150.2 ± 2.7 | 144.2 ± 2.4 | − 14.8 to 2.6 | 0.284 | 137.4 ± 2.7 | − 22.3 to − 3.3 | 0.004 |
| Sup. Nasal | 121.1 ± 3.9 | 120.7 ± 2.8 | − 11.9 to 11.0 | 1.000 | 123.3 ± 2.5 | − 8.8 to 13.2 | 1.000 |
| Nasal | 93.1 ± 2.2 | 90.5 ± 1.7 | − 11.7 to 7.8 | 1.000 | 87.1 ± 1.5 | − 12.4 to 0.4 | 0.075 |
| Inf. Nasal | 140.9 ± 3.8 | 136.7 ± 3.4 | − 16.1 to 7.7 | 1.000 | 136.9 ± 3.3 | − 16.3 to 8.3 | 1.000 |
| FAZ | |||||||
| Superficial | 241.8 ± 15.8 | 312.2 ± 17.7 | − 117.8 to − 23.4 | 0.004 | 313 ± 14.5 | − 114.5 to − 29.3 | 0.001 |
| Deep | 133.0 ± 10.5 | 182.0 ± 13.5 | − 83.4 to − 14.7 | 0.005 | 194.0 ± 10.5 | − 95.6 to − 26.4 | 0.001 |
Internal retina layers: GCL+, ganglion cell layer plus; RNFL, retinal nerve fiber layer
Significant values in bold