Table 4.
Univariable and multivariable analysis of risk factors for DR-TB in underweight TB cases
| Characteristics | Non-DR n = 1734 (%) | DR-TB n = 387 (%) | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |||
| Age (years) (n = 1725/n = 385) | ||||||
| 0–14 | 9 (0.52%) | 2 (0.52%) | 0.963 (0.203–4.557) | 0.962 | 1.022 (0.213–4.898) | 0.978 |
| 15–24 | 299 (17.33%) | 69 (17.92%) | Reference | Reference | Reference | Reference |
| 25–44 | 322 (18.67%) | 71 (18.44%) | 0.955 (0.662–1.379) | 0.808 | 0.984 (0.68–1.424) | 0.932 |
| 45–64 | 479 (27.77%) | 128 (33.25%) | 1.158 (0.835–1.605) | 0.379 | 1.138 (0.813–1.594) | 0.45 |
| > 65 | 616 (35.71%) | 115 (29.87%) | 0.809 (0.582–1.124) | 0.206 | 0.789 (0.561–1.109) | 0.173 |
| Sex (n = 1734/n = 387) | ||||||
| Female | 290 (16.72%) | 49 (12.66%) | Reference | Reference | Reference | Reference |
| Male | 1444 (83.28%) | 338 (87.34%) | 1.385 (1.001–1.917) | 0.049* | 1.458 (1.038–2.048) | 0.030* |
| Cavity (n = 1566/n = 365) | ||||||
| No | 896 (57.22%) | 206 (56.44%) | Reference | Reference | Reference | Reference |
| Yes | 670 (42.78%) | 159 (43.56%) | 1.032 (0.82–1.299) | 0.787 | 1.019 (0.807–1.286) | 0.875 |
| Smoking (n = 1423/n = 302) | ||||||
| No | 1046 (73.51%) | 220 (72.85%) | Reference | Reference | Reference | Reference |
| Yes | 377 (26.49%) | 82 (27.15%) | 0.77 (0.581–1.019) | 0.067 | 1.157 (0.802–1.669) | 0.434 |
| Drinking (n = 1407/n = 301) | ||||||
| No | 1108 (78.75%) | 245 (81.4%) | Reference | Reference | Reference | Reference |
| Yes | 299 (21.25%) | 56 (18.6%) | 0.841 (0.639–1.107) | 0.216 | 0.686 (0.455–1.033) | 0.071 |
| Co-morbidity (n = 1734/n = 387) | ||||||
| No | 1584 (91.35%) | 358 (92.51%) | Reference | Reference | Reference | Reference |
| COPD | 47 (2.71%) | 7 (1.81%) | 0.661 (0.297–1.474) | 0.312 | 0.962 (0.32–2.892) | 0.944 |
| Diabetes | 63 (3.63%) | 13 (3.36%) | 0.922 (0.502–1.693) | 0.793 | 0.959 (0.517–1.779) | 0.895 |
| Hypertension | 23 (1.33%) | 6 (1.55%) | 1.172 (0.474–2.897) | 0.732 | 1.315 (0.522–3.316) | 0.561 |
| Other co-morbidity | 97 (5.59%) | 15 (3.88%) | 0.68 (0.391–1.186) | 0.174 | 0.746 (0.347–1.604) | 0.454 |
TB, tuberculosis; DR-TB, drug-resistant tuberculosis; aOR, adjusted odds ratio; OR, odds ratio; COPD, chronic obstructive pulmonary disease
*P < 0.05; Underweight: BMI < 18.5 kg/m2