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. Author manuscript; available in PMC: 2021 Dec 6.

Published in final edited form as: Mod Pathol. 2019 Apr 11;32(9):1303–1309. doi: 10.1038/s41379-019-0268-y

Table 2.

Univariate and multivariate analysis for time to death from prostate cancer in a conservatively managed needle biopsy cohort.

	Univariate				Multivariate
Variable	IQR^* HR (95%CI)	LR χ1²	p-value	c-index^**	IQR^* HR (95%CI)	LR χ1²^†	p-value
Grade group	1.68 (1.50, 1.89)	74.56	<2.2^*10⁻¹⁶	0.716	1.38 (1.20, 1.59)	74.56	<2.2^*10⁻¹⁶
Ki-67 (continuous)	1.68 (1.49, 1.89)	47.97	4.3^*10⁻¹²	0.665	134 (1.16, 1.54)	19.85	8.38^*10⁻⁰⁶
Extent	3.21 (2.35, 4.38)	59.96	97^*10⁻¹⁵	0.690	1.74 (1.21, 2.50)	14.29	0.0002
PSA	1.66 (1.43, 1.93)	36.90	1.24^*10⁻⁰⁹	0.660	1.16 (0.98, 1.38)	2.77	0.096
Age	1.17 (0.93, 1.47)	1.81	0.178	0.527
LR χ₄² (p-value)					111.469 (<2e-16)
c-index^ (95%CI**)					0.757 (0.707, 0.808)

^*

Interquartile-range hazard ratios for continuous predictors and simple hazard ratios for categorical predictors.

^**

Harrell’s c-index,

^†

Terms added sequentially (first to last)