Table 1.
Baseline socio-demographics of participants
| Characteristics | Arm 1: HCQ + SOC |
Arm 2: SOC alone |
Total |
|---|---|---|---|
| Total randomized and analyzed | 55 | 50 | 105 |
| Age in years | |||
| Median (IQR) | 30 (26–44) | 32 (27–42) | 32 (27–43) |
| Range | 18–64 | 20–59 | 18–64 |
| Age categories, n (%) | |||
| 18–34 | 29 (52.7) | 28 (56.0) | 57 (54.3) |
| 35–59 | 25 (45.5) | 22 (44.0) | 47 (44.8) |
| ≥ 60 | 1 (1.8) | 0 | 1 (0.9) |
| Sex, n (%) | |||
| Male | 39 (70.9) | 37 (74.0) | 76 (72.4) |
| Female | 16 (29.1) | 13 (26.0) | 29 (27.6) |
| Baseline SARS COV-2 CT-valuesa | |||
| Number of observations | 17 | 17 | 34 |
| Mean (SD) | 19.0 (5.1) | 18.9 (4.9) | 18.9 (4.9) |
| Median (IQR) | 18.8 (16.1–23.0) | 19.9 (14.8–22.4) | 19.6 (14.8–23.0) |
| Range (minimum–maximum) | 9.6–27.1 | 9.6–25.5 | 9.6–27.1 |
| Comorbidity, n (%) | |||
| High blood pressureb | 2 (3.6) | 1 (2.1) | 3 (2.9) |
| Heart disease | 1 (1.8) | 0 | 1 (0.9) |
| Diabetesb | 2 (3.5) | 1 (2.0) | 3 (2.8) |
| Cigarette smokingb | 2 (3.6) | 0 | 2 (1.9) |
| Alcohol dependencyb | 7 (12.3) | 6 (12.5) | 13 (12.4) |
| HIV positiveb | 3 (5.4) | 2 (4.1) | 5 (4.8) |
HCQ hydroxychloroquine, SOC standard of care, SD standard deviation, IQR Inter-quartile range
aThe baseline SARS COV-2 CT-values were defined as the CT-values measured at patient’s enrolment. However, some participants had missing CT values at enrolment because majority of participants reported 4 days after their first positive PCR tests, and the repeat PCR test at enrolment for most of them was negative, as highlighted in this table. Only positive PCR tests could have SARS COV-2 CT-values
bMissing values: High blood pressure (n = 2), Heart disease (n = 1), Diabetes (n = 1), Cigarette smoking (n = 2), Alcohol dependency (n = 2), HIV status (n = 1), History of allergies (n = 1), Medication before admission (n = 1)