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Number of unique records retrieved from preclinical systematic searches across time. Each data point represents a Collaborative Approach to Meta-Analysis and Review of Animal Data from Experimental Studies preclinical systematic review project. tPA, tissue Plasminogen Activator; EAE, experimental automimmue encephalomyelitis; PD, Parkinsons disease; DA, dopamine antaonists, AD, Alzheimer’s disease; NP, neuropathic pain.
