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. 2021 Nov 22;12:733171. doi: 10.3389/fimmu.2021.733171

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Copyright © 2021 Zhang, Feng, Tam, Wang and Feng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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High preservation of Type I interferon gene from nasal swab and postmortem lung tissue in COVID-19. (A) A two-dimensional matrix shows the overlap genes in modules from nasal swab or lung tissue. The black rectangles represent the interesting gene module showing a large proportion of overlapped genes in either ME-A-Lung or ME-F-Nasal swab. The detailed information of intersective genes with normalized expressions from ME-F-Nasal swab and ME-A-Lung are shown in the right panel. (B) Linear relationship and adjusted rand index between ME-F (Nasal swab) and ME-A (Lung). (C, D) GO and KEGG functional enrichment analysis for ME-F (nasal swab) and ME-A (lung tissue). (E) Functional genes for corresponding enrichment annotations shown in a Sankey diagram.