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. 2021 Dec 1;14:5099–5105. doi: 10.2147/IDR.S342068

Figure 2.

Figure 2

A mean increase of formal electric charge in RBD and S1/S2 cleavage regions in the lineages monthly reported by ECDC from September 2020 to June 2021. The formal charge means the charge of the amino acids at neutral pH, in elementary charge units. The reference “wild-type’” virus B.1 was assumed (with no mutation D614G and other spike protein changes). The standard deviation of the population (vertical bar) was shown.