Table 1.
Region | Mutation | Number of Cases (Modified Lineages) | Change of Formal Charge ΔQ [e] | Time of First Detection |
---|---|---|---|---|
N-terminal domain | ins214TDR | 1 | 0 | Dec-20 |
RBD | R346K | 1 | 0 | Jan-21 |
V367F | 1 | 0 | Dec-20 | |
P384L | 1 | 0 | Dec-20 | |
Q414K | 1 | 1 | Dec-20 | |
K417N | 4 | –1 | Sep-20 | |
K417T | 2 | -1 | Dec-20 | |
N439K | 1 | 1 | Mar-21 | |
N450K | 1 | 1 | Dec-20 | |
L452Q | 1 | 0 | Dec-20 | |
L452R | 10 | 1 | Sep-20 | |
S477N | 2 | 0 | Dec-20 | |
T478K | 3 | 1 | Nov-20 | |
V483A | 1 | 1 | Feb-21 | |
E484K | 16 | 2 | Sep-20 | |
E484Q | 2 | 1 | Dec-20 | |
F490S | 2 | 0 | Dec-20 | |
S494P | 1 | 0 | Jan-21 | |
N501T | 1 | 0 | Dec-20 | |
N501Y | 12 | 0 | Sep-20 | |
E516Q | 1 | 1 | Jan-21 | |
S1/S2 junction |
Q613H | 1 | 0 | Dec-20 |
D614G | 31 | 1 | Sep-20 | |
A653V | 1 | 0 | Dec-20 | |
H655Y | 5 | –1 | Dec-20 | |
G669S | 1 | 0 | Feb-21 | |
Q677H | 2 | 0 | Dec-20 | |
ins679GIAL | 1 | 0 | Jan-21 | |
N679K | 1 | 1 | Jan-21 | |
P681H | 10 | 0 | Sep-20 | |
P681R | 4 | 1 | Dec-20 | |
A701V | 4 | 0 | Sep-20 |