TABLE 1.
Domain Assessed | Demographic Data or Test Used | Patient 1 | Patient 2† | |
---|---|---|---|---|
Visit 1 | Visit 1 | Visit 2 | ||
Age (years) | 71 | 62 | 65 | |
Years since symptom onset | ~2½ | ~2 | ~5 | |
Global Cognitive Ability | MMSE | 30/30 | 29/30 | DNT |
MoCA | 24/30§ | 25/30‡ | 22/30§ | |
Behavioral | FBI | 18/72§ | 19/72§ | DNT |
CBI–R | DNT | DNT | 61/180‖ | |
Executive Control | FAB | 15/18§ | 16/18 | 15/18§ |
Psychiatric | NPI–Q | 4/36 | 4/36 | 14/36‖ |
Praxis | WAB–R–Praxis | 59/60 | 57/60 | 50/60§ |
Parkinsonism | MDS–UPDRS III Motor subsection | 8/132 | 4/132 | 2/132 |
Calculation | Calculation subsection of MoCA | 3/3 | 3/3 | 3/3 |
Prosopagnosia | Famous Faces Recognition | 10/10 | 10/10 | 10/10 |
At the third visit, patient 2 was not a candidate for assessment secondary to the severity of her deficits, but per her husband’s ratings, she was 52/180 on the CBI–R and 12/36 on the NPI–Q.
Minimal impairment.
Mild impairment.
Moderate impairment.
CBI–R = Cambridge Behavioral Inventory—Revised. DNT = did not test. FAB = Frontal Assessment Battery. FBI = Frontal Behavioral Inventory. MDS–UPDRS III = Movement Disorders Society-sponsored version of the Unified Parkinson's Disease Rating Scale. MMSE = Mini-Mental State Examination. MoCA = Montreal Cognitive Assessment. NPI–Q = Neuropsychiatric Inventory Questionnaire. WAB–R = Western Aphasia Battery—Revised.