FIGURE 7.

Glucocorticoid receptor in the intestine, but not that in the liver, determines alcohol‐ and corticosterone‐induced neuroinflammation. Adult GR^ΔHC and GR^ΔIEC mice were fed a liquid diet with (EF) or without (PF) ethanol for 4 weeks. In some groups, animals were injected with corticosterone (Cort) daily; the other groups received the vehicle. Inflammatory responses in the hypothalamus were assessed by measuring IL‐6‐ (A) and MCP1 (B)‐specific mRNA. Values in graphs are mean ± SEM (n = 6); *p < .05 and **p < .01 for significant difference between the indicated groups; ns, not significant