| Site (name or number) | |||
|---|---|---|---|
| 1. Hardware | |||
| a. Field strength [T] | 3 T | 3 T | |
| b. Manufacturer | Siemens | Siemens | |
| c. Model (software version if available) | Skyra (VD13) | Skyra (VD13) | |
| d. RF coils: nuclei (transmit/receive), number of channels, type, body part | 32 channel 1H head coil | 10 cm 31P tuned transmit/receive surface coil | |
| e. Additional hardware | N/A | Custom‐built dynamic knee extension apparatus | |
| 2. Acquisition | |||
|---|---|---|---|
| a. Pulse sequence | PRESS | 500 μs pulse and acquire | |
| b. Volume of interest (VOI) locations | Posterior cingulate gyrus | N/A | |
| c. Nominal VOI size [cm3, mm3] | 30 × 30 × 30 mm3 | N/A | |
| d. Repetition time (T R), echo time (T E) [ms, s] | T R/T E = 2000/30 ms | T R = 2000 ms | |
|
e. Total number of excitations or acquisitions per spectrum In time series for kinetic studies i. Number of averaged spectra (NA) per time point ii. Averaging method (eg block‐wise or moving average) iii. Total number of spectra (acquired/in time series) |
64 averages |
300 total FIDs SIFT used for averaging |
|
| f. Additional sequence parameters (spectral width in Hz, number of spectral points, frequency offsets). If STEAM: mixing time (T M). If MRSI: 2D or 3D, FOV in all directions, matrix size, acceleration factors, sampling method | 1200 Hz, 1024 data points | 3000 Hz, 2048 data points | |
| g. Water suppression method | CHESS | N/A | |
| h. Shimming method, reference peak, and thresholds for “acceptance of shim” chosen | Automated B 0 field mapping followed by manual shimming of water to <14 Hz | Automated B 0 field mapping | |
| i. Triggering or motion correction method (respiratory, peripheral, cardiac triggering, incl. device used and delays) | None | None |
| 3. Data analysis methods and outputs | |||
|---|---|---|---|
| a. Analysis software | LCmodel vers 6.2 | jMRUI | |
| b. Processing steps deviating from quoted reference or product | None | SIFT pre‐processing prior to use of jMRUI | |
| c. Output measure (eg absolute concentration, institutional units, ratio), processing steps deviating from quoted reference or product | Ratios to creatine | PCr amplitude | |
| d. Quantification references and assumptions, fitting model assumptions | Default basis set | AMARES Gaussian lineshapes | |
| 4. Data quality | |||
|---|---|---|---|
| a. Reported variables (SNR, linewidth (with reference peaks)) |
SNR: 61.8 ± 6 (51‐71) FWHM: 0.043 + 0.006 (0.38‐0.57) ppm as reported by LCmodel None eliminated |
SNR and FWHM not reported | |
| b. Data exclusion criteria | SNR < 40; CRLB > 20% | SD > 10% | |
| c. Quality measures of postprocessing model fitting (eg CRLB, goodness of fit, SD of residual) | CRLB of NAA: 2 ± 0(2)% | SD: 4.5 ± 1.7% | |
| d. Sample spectrum | Figure 1 | Figure 2 |
The example above used the following paper: Zhou M, Liao H, Sreepada LP, Ladner JR, Balschi JA, Lin AP. Tai chi improves brain metabolism and muscle energetics in older adults. J Neuroimaging. 2018;28(4):359‐364. https://doi.org/10.1111/jon.12515.
Items listed in italics are details that were not included in the paper that served as the source for this example.