TABLE 1.
Characteristics of included patients.
| Good outcome | Poor outcome | P-value | |
| No. | 177 | 227 | |
| Gender (male) | 66.7% | 70.9% | 0.386 |
| Age | 63.87 (11.35) | 63.87 (11.35) | 0.058 |
| BMI | 24.02 (22.86–25.25) | 24.28 (23.44–25.61) | 0.221 |
| ONT | 171.02 (54.33) | 171.02 (54.33) | 0.091 |
| Dosage 0.9 mg/kg | 71.8% | 70.9% | 0.912 |
| Bridging therapy | 10.7% | 15.4% | 0.187 |
| NIHSS | 8.00 (5.00–12.00) | 12.00 (8.00–15.00) | <0.001 |
| Smoking | 46.9% | 41.9% | 0.315 |
| Drinking | 36.2% | 41.0% | 0.355 |
| AF | 10.7% | 10.1% | 0.871 |
| CHD | 22.0% | 26.0% | 0.413 |
| Hypertension | 38.4% | 44.5% | 0.225 |
| Diabetes | 17.5% | 20.7% | 0.448 |
| Prior Stroke | 13.0% | 17.6% | 0.216 |
| Dyslipidemia | 22.6% | 26.9% | 0.355 |
| sBP | 154.45 (18.62) | 149.53 (19.48) | 0.010 |
| dBP | 90 (14.30) | 88.3 (13.46) | 0.223 |
| Glucose | 5.58 (4.84–7.14) | 6.33 (5.26–8.30) | <0.001 |
| Homocysteine | 14.3 (10.90–20.90) | 15.90 (11.60–24.30) | 0.041 |
| Cholesterol | 4.78 (1.19) | 4.78 (0.92) | 0.639 |
| Triglyceride | 1.36 (0.95–1.94) | 1.16 (0.85–1.71) | 0.279 |
| LDL-C | 2.92 (0.91) | 2.9 (0.71) | 0.795 |
| HDL-C | 1.22 (1.03–1.43) | 1.24 (1.04–1.50) | 0.194 |
| NT-proBNP | 145.00 (70.65–526.50) | 411.00 (128.00–1690.00) | <0.001 |
Categorical variables were expressed as percentage, %; Continuous variables conform to normal distribution were expressed as mean and SD, Mean (SD); Continuous variables not conform to normal distribution were expressed as median and IQR, Median (Q1–Q3). Gender (male), BMI (kg/m2), ONT (min), Homocysteine (μmol/L), Glucose (mmol/L), BP (mmHg), Cholesterol (mmol/L), Triglyceride (mmol/L), LDL-C (mmol/L), HDL-C (mmol/L), NT-proBNP (pg/mL). BMI, Body mass index; ONT, Onset to needle time; NIHSS, The National Institutes of Health Stroke Scale; AF, Atrial fibrillation; CHD, Coronary heart disease; sBP, Systolic blood pressure; dBP, Diastolic blood pressure; LDL-C, Low density lipoprotein cholesterin; HDL-C, High density lipoprotein cholesterin; NT-proBNP, The N-terminal of the prohormone brain natriuretic peptide; SD, Standard deviation; IQR, Interquartile range.