TABLE 2.
Results of univariate analysis.
| Functional outcome | Mortality | Hemorrhagic transformation | Early neurologic deterioration | |||||||||
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| P-value | OR | 95%CI | P-value | OR | 95%CI | P-value | OR | 95%CI | P-value | OR | 95%CI | |
| Gender | 0.359 | 1.220 | 0.80–1.86 | 0.908 | 1.049 | 0.47–2.36 | 0.140 | 1.560 | 0.86–2.82 | 0.521 | 1.314 | 0.57–3.02 |
| Age | 0.059 | 1.017 | 1.00–1.03 | 0.056 | 1.035 | 1.00–1.07 | 0.925 | 0.999 | 0.98–1.02 | 0.895 | 0.998 | 0.97–1.03 |
| BMI | 0.221 | 1.043 | 0.97–1.12 | 0.692 | 0.974 | 0.86–1.11 | 0.291 | 1.048 | 0.96–1.14 | 0.566 | 1.037 | 0.92–1.17 |
| ONT | 0.092 | 1.003 | 1.00–1.01 | 0.155 | 1.005 | 1.00–1.01 | 0.155 | 1.003 | 1.00–1.01 | 0.375 | 1.003 | 1.00–1.01 |
| Dosage 0.9 mg/kg | 0.855 | 0.960 | 0.62–1.48 | 0.871 | 0.935 | 0.41–2.11 | 0.631 | 1.151 | 0.65–2.05 | 0.967 | 0.983 | 0.44–2.20 |
| Bridging therapy | 0.172 | 1.516 | 0.83–2.75 | 0.575 | 0.704 | 0.21–2.40 | 0.006 | 2.464 | 1.30–4.68 | 0.123 | 2.023 | 0.83–4.95 |
| NIHSS | <0.001 | 1.124 | 1.08–1.17 | <0.001 | 1.112 | 1.07–1.16 | 0.150 | 1.025 | 0.99–1.06 | 0.076 | 0.939 | 0.88–1.01 |
| Smoking | 0.311 | 0.815 | 0.55–1.21 | 0.031 | 2.336 | 1.08–5.05 | 0.031 | 1.757 | 1.05–2.94 | 0.804 | 0.910 | 0.43–1.91 |
| Drinking | 0.325 | 1.225 | 0.82–1.84 | 0.602 | 1.221 | 0.58–2.59 | 0.001 | 2.463 | 1.47–4.13 | 0.434 | 0.732 | 0.34–1.60 |
| AF | 0.844 | 0.938 | 0.49–1.78 | 0.004 | 3.636 | 1.50–8.79 | 0.058 | 2.013 | 0.98–4.15 | 0.892 | 0.918 | 0.27–3.16 |
| CHD | 0.358 | 1.243 | 0.78–1.97 | 0.232 | 1.625 | 0.73–3.60 | 0.657 | 0.871 | 0.47–1.60 | 0.834 | 1.094 | 0.47–2.53 |
| Hypertension | 0.220 | 1.285 | 0.86–1.92 | 0.833 | 0.921 | 0.43–1.97 | 0.010 | 1.967 | 1.18–3.29 | 0.026 | 2.354 | 1.11–4.99 |
| Diabetes | 0.421 | 1.230 | 0.74–2.03 | 0.920 | 1.049 | 0.41–2.66 | 0.309 | 1.373 | 0.75–2.53 | 0.021 | 2.512 | 1.15–5.49 |
| Prior Stroke | 0.205 | 1.432 | 0.82–2.50 | 0.385 | 0.581 | 0.17–1.98 | 0.526 | 1.243 | 0.63–2.43 | 0.549 | 1.331 | 0.52–3.39 |
| Dyslipidemia | 0.326 | 1.259 | 0.80–1.99 | 0.276 | 1.555 | 0.70–3.44 | 1.000 | 1.000 | 0.56–1.80 | 0.334 | 1.476 | 0.67–3.25 |
| sBP | 0.011 | 1.014 | 1.00–1.02 | 0.598 | 1.005 | 0.99–1.03 | 0.400 | 1.006 | 0.99–1.02 | 0.063 | 1.020 | 1.00–1.04 |
| dBP | 0.223 | 1.009 | 0.99–1.02 | 0.516 | 0.991 | 0.96–1.02 | 0.658 | 1.004 | 0.99–1.02 | 0.883 | 0.998 | 0.97–1.02 |
| Glucose | <0.001 | 1.157 | 1.07–1.26 | 0.015 | 1.144 | 1.03–1.27 | 0.092 | 1.075 | 0.99–1.17 | 0.001 | 1.194 | 1.08–1.32 |
| Homocysteine | 0.049 | 1.014 | 1.00–1.03 | 0.041 | 1.019 | 1.00–1.04 | 0.239 | 1.009 | 0.99–1.02 | 0.796 | 0.997 | 0.97–1.02 |
| Cholesterol | 0.977 | 0.997 | 0.83–1.20 | 0.101 | 1.306 | 0.95–1.80 | 0.022 | 0.741 | 0.57–0.96 | 0.786 | 0.953 | 0.68–1.34 |
| Triglyceride | 0.280 | 0.890 | 0.72–1.10 | 0.477 | 0.848 | 0.54–1.34 | 0.530 | 0.911 | 0.68–1.22 | 0.168 | 1.262 | 0.91–1.76 |
| LDL-C | 0.753 | 1.039 | 0.82–1.32 | 0.028 | 1.565 | 1.05–2.34 | 0.005 | 0.606 | 0.43–0.86 | 0.910 | 0.975 | 0.62–1.52 |
| HDL-C | 0.195 | 1.462 | 0.82–2.60 | 0.112 | 2.125 | 0.84–5.39 | 0.503 | 0.772 | 0.36–1.65 | 0.492 | 0.674 | 0.22–2.07 |
| ln(NT-proBNP) | <0.001 | 1.451 | 1.26–1.67 | <0.001 | 1.788 | 1.38–2.31 | <0.001 | 1.341 | 1.14–1.58 | 0.676 | 1.051 | 0.83–1.32 |
OR, Odds ratio; 95% CI, 95% confidence interval; BMI, Body mass index; ONT, Onset to needle time; NIHSS, The National Institutes of Health Stroke Scale; AF, Atrial fibrillation; CHD, Coronary heart disease; sBP, Systolic blood pressure; dBP, Diastolic blood pressure; LDL-C, Low density lipoprotein cholesterin; HDL-C, High density lipoprotein cholesterin; NT-proBNP, N-terminal of the prohormone brain natriuretic peptide.