Table 3.
Results of Correlation Analysis Between the Mean FA Value of Each Cluster and the Clinical Severity Indicator as Well as Neurocognitive Assessment Scores
| Brain Areas | OAHI (Events/hr) | FIQ | VIQ | PIQ | Attention | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| MG | SG | MG | SG | MG | SG | MG | SG | MG | SG | |
| Cluster 2 | r = −0.20 (p= 0.35) | r = −0.18 (p= 0.28) | r = 0.24 (p = 0.28) | r = 0.24 (p= 0.15) | r = 0.28 (p= 0.19) | r = 0.40 (p= 0.01) | r = 0.10 (p=0.65) | r = 0.05 (p= 0.75) | r = −0.15 (p= 0.51) | r = −0.27 (p= 0.11) |
| Cluster 3 | r = −0.21 (p= 0.35) | r = −0.16 (p= 0.33) | r = 0.16 (p = 0.48) | r = 0.36 (p= 0.03) | r = 0.32 (p= 0.14) | r = 0.38 (p= 0.02) | r = 0.02 (p=0.94) | r = 0.28 (p= 0.10) | r = −0.14 (p= 0.54) | r = −0.35 (p= 0.04) |
| Cluster 4 | r = −0.20 (p= 0.36) | r = −0.39 (p= 0.02) | r = 0.02 (p = 0.93) | r = 0.44 (p= 0.008) | r = 0.13 (p= 0.57) | r = 0.47 (p=0.004) | r = −0.06 (p=0.98) | r = 0.19 (p= 0.27) | r = −0.21 (p= 0.34) | r = −0.19 (p= 0.26) |
Note: p < 0.05 considered statistically significant and presented in bold.
Abbreviations: FA, fractional anisotropy; MG, mild OSA group; SG, moderate-severe OSA group; OAHI, obstructive apnea hypopnea index; VIQ, verbal skills IQ; PIQ, performance skills IQ; FIQ, full scale IQ; cluster, brain regions with decreased FA values for SG compared to HC; HC, healthy control group.