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. 2021 Dec 2;566:122–135. doi: 10.1016/j.virol.2021.11.012

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Fig. 8 — Intracranial infection with m-β-CoV-RSA59 induced higher infiltrating Ly6G + neutrophils and MHC II⁺subsets within CD45^hiand CD45^lopopulations and did not alter CD11b⁺myeloid cell population by number while in the brain at 5 days post-infection. Brains from naïve or mock-infected (day 15–16) and virus-infected (day 5) mice were harvested for flow cytometric analysis. A–D: Representative flow cytometry plots indicating percentages of Ly6G⁺ cells within CD45^hi/lo populations and cell numbers (C, D) in brains after gating on live cells. E–H: Representative flow cytometry plots indicating percentages of CD11b⁺ cells within CD45^hi/lo populations and cell number (G, H) in brains after gating on live cells. I–L: Representative flow cytometry plots indicating percentages of MHC II ⁺ cells within CD45^hi/lo populations and cell number (K, L) in brains after gating on live cells. Graphs represent data from three to six biological replicates. Asterix (*) denotes differences that are statistically significant by Student's unpaired t-test analysis (**, p < 0.01; ***, p < 0.001).