Table 2.
Results of preparation and endoscopic findings
| Standard | Split group | |||
| Variable | Day 1 | Day 2 | P value | |
| No. of patients | 78 | 77 | ||
| Time to take the solution (min) | 115.3 ± 56.7 | 56.2 ± 23.1 | 59.1 ± 27.6 | <0.001* |
| Time to first defecation (min, mean±SD) | 54.8 ± 34.2 | 91.1 ± 56.3 | 47.1 ± 26.2** | 0.12* |
| Frequency of defecation (times, mean±SD) | 12.4 ± 4.3 | 6.8 ± 4.0 | 10.1 ± 4.7** | <0.01* |
| Time to preparation (min, mean±SD) | 198.1 ± 93.8 | 175.9 ± 82.9 | 0.12* | |
| Time to last defecation before going to bed | 281.7 ± 83.5 | |||
| Preparation scale of last defecation (day 1) | ||||
| (watery clear/clear/muddy/soft stool/normal) | (18/40/14/1/1) | |||
| Elapsed time from last fluid intake to | 229 ± 115 | 233 ± 118 | 0.82* | |
| colonoscopy (min, mean+SD) | ||||
| Cecal intubation rate (n,%) | 78 (100) | 77 (100) | ||
| Insertion time (min, mean±SD) | 8.8 ± 6.0 | 9.6 ± 5.5 | 0.41 | |
| Feeling of peristalsis (n, %) | 15 (19.2) | 12 (16.0) | 0.60 | |
| Optimal visibility grade (0/1/2) | 45/24/9 | 39/19/17 | 0.17 | |
| BBPS (PP) | ||||
| Right colon (mean±SD) | 2.1 ± 1.0 | 2.1 ± 0.7 | 0.67 | |
| Transverse colon (mean±SD) | 2.3 ± 1.0 | 2.5 ± 0.6 | 0.12 | |
| Left colon (mean±SD) | 2.4 ± 1.0 | 2.6 ± 0.6 | 0.04 | |
| Successful bowel cleansing (n, %)*** | 65 (83.3) | 69 (92.0) | 0.10 | |
| No. with additional PEG intake or enema (n, %) | 9 (11.5) | 1 (1.3) | 0.01 | |
BBPS: Boston bowel preparation scale
PP: per-protocol analysis
* Same-day group vs. split-dose group (Day 2).
** P<0.001, split-dose group (Day 1) vs. split-dose group (Day 2).
*** Difference and 95% confidence interval in the successful bowel preparation rate between the same-day group and the split-dose group was 8.7% (–1.6% to 19.0%).