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. 2021 Nov 23;112:106633. doi: 10.1016/j.cct.2021.106633

Table 1.

Pre-COVID MACRO risk stratification.

Medical Criteria
Functional Criteria
Psychosocial Criteria
CVD based on medical record Risk based on baseline assessments Risk based on baseline assessments
High Risk
  • LVEF<40%

  • s/p cardiac arrest or sudden death

  • Complex ventricular dysrhythmias (ventricular tachycardia, frequent [> 6/min] multiform PVCs)

  • s/p MI without revascularization

  • s/p MI or cardiac surgery complicated by cardiogenic shock

  • Heart Transplant, left ventricular assist device

  • Signs/symptoms including angina pectoris, dizziness, lightheadedness or dyspnea

  • Moderate to high valvular heart disease

  • Severe pulmonary hypertension (PAP ≥50 mmHg)

  • Five or more comorbidities that confound CVD management

  • Presence of ≥4 FRIDs

High Risk
  • SPPB ≤4

  • Gait speed <0.8 m/s

  • Grip strength <10 kg

  • Functional capacity <3 METs

  • Significant falling history





High Risk
  • Readiness to change: Precontemplation

  • Mood: PHQ >10 or response >0 for question 9

  • Cognition: Short Blessed 10+

  • Literacy: REALM <4






Moderate Risk
  • LVEF = 40–49%

  • MI with PCI - Incomplete revascularization

  • MI with CABG - Incomplete revascularization

  • Elective PCI/Stent/PTCA – Incomplete revascularization

  • Elective CABG – Incomplete revascularization

  • Presence of 2-3 FRIDs

Moderate Risk
  • SPPB 5–7

  • Gait speed 0.8–1.0 m/s

  • Grip strength 10–14.5 kg

  • Approximate functional capacity level 3–5 METs

Moderate Risk
  • Readiness to change: Contemplation

  • Mood: PHQ-9 6–10

  • Cognition: Short Blessed 5–9

  • Literacy: REALM 4–6

Low Risk
  • LVEF≥50%

  • No evidence of arrhythmia

  • MI with PCI - Complete revascularization

  • MI with CABG - Complete revascularization

  • Elective PCI/Stent/PTCA – Complete revascularization

  • Elective CABG – Complete revascularization

  • Absence of symptoms or signs of HF or ischemia

  • Normal hemodynamics and ECG

  • Presence of ≤1 FRIDs

Low Risk
  • SPPB ≥8

  • Gait speed >1.0 m/s

  • Grip strength >14.5 kg

  • Approximate function level > 5 METS

Low Risk
  • Readiness to change: Preparation, Action, and Maintenance

  • Mood: PHQ-9 < 6

  • Cognition: Short blessed 0–4

  • Literacy: REALM ≥7

LVEF-Left ventricular ejection fraction; MI-myocardial infaction; PCI-percutaneous coronary intervention; CABG-coronary artery bypass grafting surgery; PTCA-percutaneous transluminal coronary angioplasty; ECG-electrocardiogram; FRIDs-Fall risk-increasing drugs; SPPB-Short Physical Performance Battery; METs-metabolic equivalents; PHQ-Patient Health Questionnaire; REALM-Rapid Estimate of Adult Literacy in Medicine.

FRIDs: Fall risk-increasing drugs (includes: opioids, antipsychotics [lithium excluded], anxiolytics, hypnotics and sedatives, antidepressants, vasodilators used in cardiac disease, antihypertensives, and dopaminergic agents).

Estimate of METs is based on the Duke Activity Status Index.