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. 2021 Dec 6;53(12):1636–1648. doi: 10.1038/s41588-021-00973-1

Extended Data Fig. 7. Colocalization analysis with FTD subtypes.

Extended Data Fig. 7

Top associated SNPs in the ALS GWAS were selected for colocalization analysis between ALS and FTD subtypes using COLOC. In the top panel, point height is the two-sided -log10(P-value) of the top-associated SNP in the ALS GWAS. In the bottom panel, association P-values of these SNPs with FTD subtypes are shown by color. The Bayesian posterior probability for a shared causal variant between traits (PPH4) is depicted by a connection between points.

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