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. 2021 Dec 6;53(12):1636–1648. doi: 10.1038/s41588-021-00973-1

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© The Author(s) 2021, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 1 — Genome-wide association statistics obtained by inverse-variance weighted meta-analysis of the stratified SAIGE logistic mixed model regression in European ancestry cohorts. Y-axis corresponds to the two-tailed -log₁₀(P-value), x-axis corresponds to the genomic coordinates (GRCh37). Loci containing a genome-wide significant SNP are highlighted in red. SNP IDs are the top associated SNPs in each locus. The dotted horizontal line reflects the threshold for genome-wide significance (P = 5 × 10⁻⁸).

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