Table 2.
Effect of D. salina biomass and its isolated polar and carotenoid fractions on the mean escape latency time in Morris water maze in dementia-induced rats.
| GROUPS | Acquisition Phase MWM |
||
|---|---|---|---|
| Mean Escape Latency time (sec) |
|||
| 1st Day | 2nd Day | 3rd Day | |
| Normal | 29.47 ± 4.24 | 28.05 ± 1.63 | 26.25 ± 1.83 |
| D-Gal | 52. 45. ± 5.52a | 40.6 ± 2.59a | 38.9 ± 3.61a |
| D-Gal + BDS | 40.04 ± 2.22 | 37.45 ± 2.71 | 27.7 ± 1.47b |
| D-Gal + PDS | 37.64 ± 5.53 | 34.75 ± 2.02 | 26.55 ± 1.44b |
| D-Gal + CDS | 29.92 ± 4.18b | 31.00 ± 1.31b | 21.35 ± 2.61b |
| D-Gal + ZH | 28.89 ± 3.32b | 29.56 ± 2.01b | 23.88 ± 1.54b |
Data was expressed as mean ± SEM, n = 6 rats/group.
a
Significantly different from the normal control on the corresponding day at P < 0.05.
b
Significantly different from the AD group on the corresponding day at P < 0.05.