. 2021 Nov 29;8:1899–1908. doi: 10.1016/j.toxrep.2021.11.021

Table 3.

Effect of D. salina biomass and its isolated polar and carotenoid fractions on the brain neurotransmitters levels in dementia-induced rats.

GROUPS	Neurotransmitter content (ug/g tissue)			Metabolites contents (ug/g tissue)
GROUPS	5-HT	NE	DOP	5-HIAA	HVA	DOPAC
Normal	0.32 ± 0.02	0.21 ± 0.002	0.859 ± 0.005	0.33 ± 0.04	0.104 ± 0.004	0.090 ± 0.003
D-Gal	0.14 ± 0.012^a	0.15 ± 0.009^a	0.281 ± 0.006^a	0.66 ± 0.01^a	0.098 ± 0.004	0.132 ± 0.004^a
D-Gal + BDS	0.17 ± 0.01^a	0.19 ± 0.006^ab	0.324 ± 0.008^ab	0.63 ± 0.02^a	0.861 ± 0.02	0.120 ± 0.03^a
D-Gal + PDS	0.2 ± 0.02^ab	0.17 ± 0.004^ab	0.454 ± 0.003^ab	0.56 ± 0.03^a	0.972 ± 0.06	0.109 ± 0.009^a
D-Gal + CDS	0.26 ± 0.006^ab	0.20 ± 0.01^b	0.580 ± 0.02^ab	0.45 ± 0.01^ab	0.898 ± 0.03	0.099 ± 0.04^ab
D-Gal + ZH	0.23 ± 0.005^ab	0.18 ± 0.02^b	0.670 ± 0.01^ab	0.48 ± 0.01^ab	0.980 ± 0.04	0.091 ± 0.03^ab

Data was expressed as mean ± SEM, n = 6 rats/group.

^a Significantly different from the normal control.

^b Significantly different from the AD group at P < 0.05.