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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Curr Opin Struct Biol. 2021 Jul 2;71:65–70. doi: 10.1016/j.sbi.2021.05.015

Table 3.

Summary of mutations in FOXA1

GENE MUTATION TYPE FUNCTIONAL DOMAIN PREDICTED IMPACT
FOXA1 Missense Wing 2 (Forkhead) Reinforce transcriptional program
Missense β strand 3 (Forkhead) Novel DNA binding pattern