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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Curr Opin Immunol. 2021 Aug 16;73:16–24. doi: 10.1016/j.coi.2021.07.007

Figure 2: Monocyte fates induced by inflammation.

Figure 2:

A variety of inflammatory signals can act on myeloid progenitor cells or monocytes to induce differentiation into specialized monocyte-derived populations. Signals can act in a direct (e.g. Toll-like receptors) fashion or through indirect mechanisms (e.g. cytokines) to promote these cell fates. Different combinations of markers and gene expression patterns allow for the identification of monocyte-derived cell populations. TLR, Toll-like receptor; Hh colitis, Helicobater hepaticus-induced colitis; CHIKV, chikungunya virus; T. gondii, Toxoplasma gondii; MDP, Monocyte-DC Progenitor; GMP, Granulocyte Macrophage Progenitor; SatM, segregated-nucleus-containing atypical monocyte; iHPC, inflammatory hemophagocyte; moDC, monocyte-derived dendritic cell.