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. 2021 Sep 23;26(12):1006–e2129. doi: 10.1002/onco.13949
Disease Advanced cancer, prostate cancer
Stage of Disease/Treatment Metastatic/advanced
Prior Therapy No designated number of regimens
Type of Study Phase II, randomized
Primary Endpoint Safety, bone metabolism markers
Secondary Endpoint Overall survival, PSA–progression‐free survival, radiographic progression‐free survival
Additional Details of Endpoints or Study Design Post hoc analysis values of PSA‐PFS2 (time from start of protocol therapy to PSA progression on subsequent therapy) and TTNT
Investigator's Analysis Active and should be pursued further