Figure 3: Juvenile SD-Nrxn1tm1Sage KO males display increased locomotion in the open field.
Biallelic mutation of Nrxn1α results in increased locomotive behavior in males, but not females, as shown by distance traveled in the open field. 2Way ANOVA with Tukey’s posthoc within sex: * = p < 0.05, ** = p < 0.01 (N = 8 WT males, 8 Het males, 6 KO males, 8 WT females, 8 Het females, 8 KO females).