Fig. 3.
Gene expression analysis of livers of NASH mice treated with u-ADSCs. The u-ADSCs (1 × 106 cells) were injected into the splenic subcapsule of NASH mice on week 24 and 26 of AT-HF diet feeding. Control mice received PBS. Liver tissues were sampled on week 28. RNA was isolated from liver tissues for qRT-PCR and DNA microarray analyses. (A) Expression of albumin assessed by qRT-PCR; bars represent mean ± SE, u-ADSCs: n = 4, PBS: n = 5. (B) Heatmap and dendrogram depicting an unsupervised clustering analysis of 8148 filtered genes whose expression for which the p-value of the log-ratio was lower than 0.05, and genes were excluded if the percent of missing spot values among arrays exceeded 1%; centered correlation and average linkage was used for clustering.