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. 2021 Sep 29;10(19):e021024. doi: 10.1161/JAHA.121.021024

Table 1.

Deaths and DALYs for IHD Attributable to Modifiable Risk Factors, and PAF Both Globally and in Low‐ and Middle‐Income Countries in 2019

Low‐income Lower‐middle Upper‐middle Globally

Attributable number

(in thousand) (95% UI*)

PAF (%) (95% UI) Rank

Attributable number

(in thousand) (95% UI*)

PAF (%) (95% UI) Rank

Attributable number

(in thousand) (95% UI*)

PAF (%) (95% UI) Rank

Attributable number

(in thousand) (95% UI*)

PAF (%) (95% UI) Rank
Death
Environmental/occupational risks

128.5

(106.9 to 153.0)

41.7

(38.1 to 45.9)

1192.8

(1040.6 to 1350.6)

35.2

(32.0 to 38.2)

1017.8

(865.2 to 1181.2)

27.8

(24.7 to 31.0)

2615.8

(2296.2 to 2939.7)

28.6

(25.8 to 31.6)

Air pollution

106.5

(87.8 to 127.6)

34.6

(31.2 to 39.0)

928.0

(804.2 to 1049.6)

27.4

(25.0 to 30.0)

689.5

(580.2 to 802.0)

18.8

(16.6 to 21.1)

1843.2

(1605.7 to 2080.5)

20.2

(17.9 to 22.4)

Particulate matter pollution

106.5

(87.8 to 127.6)

34.6

(31.2 to 39.0)

928.0

(804.2 to 1049.6)

27.4

(25.0 to 30.0)

689.5

(580.2 to 802.0)

18.8

(16.6 to 21.1)

1843.2

(1605.7 to 2080.5)

20.2

(17.9 to 22.4)

Ambient particulate matter pollution

22.6

(13.1 to 35.2)

7.4

(4.2 to 11.2)

11

612.9

(483.3 to 737.3)

18.1

(14.8 to 21.2)

4

580.2

(477.3 to 686.4)

15.8

(13.5 to 18.0)

7

1332.0

1086.9 to 1557.2)

14.6

(12.2 to 16.7)

7
Household air pollution from solid fuels

83.9

(63.4 to 108.2)

27.2

(21.8 to 33.6)

3

315.1

(211.8 to 440.1)

9.3

(6.4 to 12.8)

10

109.2

(55.5 to 186.3)

3.0

(1.5 to 5.1)

21

511.2

(348.4 to 714.6)

5.6

(3.8 to 7.8)

14
Suboptimal temperature

16.5

(9.4 to 22.5)

5.4

(2.9 to 7.1)

173.9

(88.0 to 234.8)

5.1

(2.7 to 6.8)

269.6

(186.8 to 364.4)

7.4

(5.2 to 9.9)

596.8

(414.3 to 763.3)

6.5

(4.6 to 8.3)

High temperature

2.1

(−4.2 to 4.6)

0.7

(−1.3 to 1.5)

26

29.2

(−39.0 to 70.9)

0.9

(−1.2 to 2.1)

26

8.8

(−3.4 to 17.9)

0.2

(−0.1 to 0.5)

26

43.3

(−42.1 to 95.3)

0.5

(−0.5 to 1.0)

26
Low temperature

14.5

(9.6 to 19.8)

4.7

(3.2 to 6.2)

18

145.8

(94.9 to 195.6)

4.3

(2.8 to 5.7)

21

261.5

(176.8 to 358.7)

7.1

(4.9 to 9.6)

11

555.5

(391.6 to 721.3)

6.1

(4.4 to 7.9)

12
Other environmental risks

18.2

(11.4 to 26.5)

5.9

(3.8 to 8.3)

207.1

(133.2 to 292.4)

6.1

(4.1 to 8.3)

153.2

(87.3 to 235.9)

4.2

(2.4 to 6.3)

413.0

(242.8 to 615.7)

4.5

(2.7 to 6.6)

Lead exposure

18.2

(11.4 to 26.5)

5.9

(3.8 to 8.3)

14

207.1

(133.2 to 292.4)

6.1

(4.1 to 8.3)

15

153.2

(87.3 to 235.9)

4.2

(2.4 to 6.3)

17

413.0

(242.8 to 615.7)

4.5

(2.7 to 6.6)

17
Behavioral risks

189.2

(154.9 to 228.1)

61.5

(54.1 to 68.1)

2215.5

(1932.4 to 2499.4)

65.4

(58.7 to 71.0)

2383.8

(2049.0 to 2701.1)

65.1

(58.5 to 71.1)

5896.9

(5170.3 to 6632.0)

64.5

(57.8 to 70.6)

Tobacco

48.6

(41.1 to 57.0)

15.8

(14.6 to 17.1)

734.7

(656.5 to 807.9)

21.7

(20.5 to 22.9)

887.2

(795.7 to 988.6)

24.2

(22.8 to 25.8)

1998.2

(1840.4 to 2155.8)

21.9

(20.8. 23.1)

Smoking

39.4

(33.4 to 46.3)

12.8

(11.8 to 13.9)

7

597.7

(537.0 to 658.1)

17.7

(16.7 to 18.7)

6

748.4

(670.6 to 831.6)

20.4

(19.1 to 21.9)

4

1682.0

(1558.4 to 1805.3)

18.4

(17.5 to 19.5)

4
Secondhand smoke

10.9

(8.4 to 13.8)

3.6

(2.9 to 4.3)

21

166.5

(134.0 to 201.7)

4.9

(4.0 to 5.9)

18

178.1

(141.4 to 217.5)

4.9

(4.0 to 5.8)

16

397.4

(319.9 to 477.6)

4.3

(3.6 to 5.2)

18
Alcohol use

−5.4

(−9.4 to −1.5)

−1.8

(−3.0 to −0.5)

27

−30.8

(−65.3 to 5.5)

−0.9

(−2.0 to 0.2)

27

−34.9

(−98.1 to 27.1)

−1.0

(−2.6 to 0.7)

27

−108.0

(−252.6 to 36.5)

−1.2

(−2.8 to 0.4)

27
Dietary risks

166.6

(130.2 to 206.4)

54.1

(45.0 to 62.4)

1857.1

(1523.7 to 2170.3)

54.9

(45.7 to 62.4)

1925.4

(1547.2 to 2307.2)

52.6

(43.3 to 60.9)

4877.1

(3990.6 to 5749.3)

53.4

(44.2 to 61.2)

Diet low in fruits

19.2

(7.7 to 29.4)

6.2

(2.6 to 9.0)

13

222.4

(98.5 to 323.8)

6.6

(2.9 to 9.4)

13

131.3

(45.3 to 210.1)

3.6

(1.2 to 5.6)

19

436.5

(179.4 to 659.3)

4.8

(1.9 to 7.1)

16
Diet low in vegetables

26.9

(16.5 to 37.6)

8.7

(5.5 to 11.9)

10

192.7

(106.2 to 277.2)

5.7

(3.2 to 8.0)

16

75.5

(38.5 to 108.4)

2.1

(1.1 to 3.0)

24

358.3

(195.9 to 513.6)

3.9

(2.1 to 5.6)

19
Diet low in legumes

36.6

(8.4 to 61.9)

11.9

(2.8 to 19.3)

8

441.0

(99.5 to 723.4)

13.0

(3.0 to 21.0)

8

410.6

(85.8 to 660.6)

11.2

(2.3 to 18.1)

10

1116.4

(252.0 to 1815.3)

12.2

(2.8 to 19.7)

9
Diet low in whole grains

50.2

(19.2 to 67.9)

16.3

(6.2 to 21.5)

5

540.9

(213.2 to 711.1)

16.0

(6.2 to 20.9)

7

594.3

(219.6 to 781.5)

16.2

(5.9 to 21.1)

6

1459.1

(550.8 to 1908.0)

16.0

(6.0 to 20.8)

6
Diet low in nuts and seeds

16.4

(8.7 to 23.2)

5.3

(2.8 to 7.3)

16

263.3

(149.3 to 352.0)

7.8

(4.4 to 10.3)

12

189.9

(83.7 to 278.7)

5.2

(2.3 to 7.5)

14

546.6

(279.3 to 757.4)

6.0

(3.1 to 8.2)

13
Diet high in processed meat

3.8

(0.7 to 10.8)

1.2

(0.2 to 3.4)

25

46.9

(21.0 to 91.1)

1.4

(0.6 to 2.7)

25

63.8

(12.1 to 132.4)

1.7

(0.3 to 3.6)

25

197.2

(47.0 to 377.6)

2.2

(0.5 to 4.2)

24
Diet high in sugar‐sweetened beverages

7.2

(5.6 to 9.0)

2.3

(1.9 to 2.8)

24

62.5

(44.0 to 79.6)

1.8

(1.3 to 2.3)

24

80.8

(54.2 to 104.8)

2.2

(1.5 to 2.8)

23

193.1

(127.4 to 248.5)

2.1

(1.4 to 2.7)

25
Diet low in fiber

11.4

(4.6 to 19.0)

3.7

(1.5 to 6.2)

20

166.6

(74.4 to 269.9)

4.9

(2.2 to 7.7)

19

96.9

(37.4 to 171.7)

2.6

(1.0 to 4.6)

22

348.9

(147.6 to 568.3)

3.8

(1.6 to 6.2)

21
Diet low in seafood omega‐3 fatty acids

12.5

(4.1 to 17.7)

4.1

(1.3 to 5.5)

19

136.3

(52.0 to 184.5)

4.0

(1.6 to 5.3)

22

132.7

(69.4 to 172.5)

3.6

(1.9 to 4.5)

18

337.3

(165.6 to 435.7)

3.7

(1.8 to 4.7)

23
Diet low in polyunsaturated fatty acids

14.8

(2.1 to 29.9)

4.8

(0.7 to 9.6)

17

166.7

(19.5 to 340.4)

4.9

(0.6 to 7.7)

17

130.3

(16.7 to 268.8)

3.6

(0.4 to 7.3)

20

346.2

(44.2 to 707.3)

3.8

(0.5 to 7.7)

22
Diet high in trans fatty acids

16.7

(2.7 to 26.1)

5.4

(0.8 to 8.3)

15

269.4

(31.6 to 371.7)

8.0

(1.0 to 10.7)

11

218.5

(28.3 to 308.9)

6.0

(0.8 to 8.4)

12

645.0

(75.9 to 882.3)

7.1

(0.8 to 9.5)

11
Diet high in sodium

21.9

2.3 59.3

7.1

(0.8 to 19.6)

12

215.7

(24.6 to 564.6)

6.4

(0.7 to 16.6)

14

431.5

(138.9 to 855.3)

11.8

(3.9 to 23.3)

9

777.2

(185.3 to 1773.1)

8.5

(2.1 to 19.4)

10
Diet high in red meat

7.5

(0.7 to 15.2)

2.4

(0.2 to 4.6)

23

69.8

(9.2 to 133.3)

2.1

(0.3 to 3.9)

23

180.2

(29.7 to 337.6)

4.9

(0.8 to 9.1)

15

351.2

(55.9 to 642.7)

3.8

(0.6 to 7.1)

20
Low physical activity

10.8

(3.7 to 25.3)

3.5

(1.2 to 8.0)

22

154.5

(57.1 to 331.7)

4.6

(1.7 to 9.5)

20

205.8

(74.8 to 417.3)

5.6

(2.1 to 11.4)

13

486.8

(175.7 to 1003.3)

5.3

(1.9 to 11.0)

15
Metabolic risks

242.1

(201.4 to 285.5)

78.6

(72.2 to 85.0)

2806.8

(2475.5, to3126.9)

82.9

(76.9 to 88.7)

2999.1

(2627.5 to 3339.7)

81.9

(74.8 to 88.3)

7526.9

(6657.2 to 8311.7)

82.4

(75.7 to 88.5)

High systolic blood pressure

161.3

(126.5 to 198.8)

52.4

(44.3 to 60.3)

1

1856.1

(1533.8 to 2194.9)

54.8

(46.7 to 63.2)

1

1964.3

(1553.3 to 2381.2)

53.6

(42.9 to 63.7)

1

4861.6

(3927.2 to 5853.4)

53.2

(43.4 to 62.8)

1
High LDL cholesterol

114.8

(85.3 to 148.8)

37.3

(29.1 to 46.1)

2

1374.2

(1064.8 to 1717.1)

40.6

(32.3 to 49.5)

2

1549.5

(1141.7 to 1988.3)

42.3

(31.6 to 53.6)

2

3784.3

(2826.6 to 4824.7)

41.4

(31.5 to 52.1)

2
High fasting plasma glucose

68.8

(40.5 to 109.7)

22.4

(13.3 to 35.2)

4

923.2

(545.5 to 1439.0)

27.3

(16.6 to 42.3)

3

810.1

(460.6 to 1292.0)

22.1

(12.7 to 34.5)

3

2353.4

(1361.2 to 3701.9)

25.8

(15.0 to 40.3)

3
High body‐mass index

40.8

(21.1 to 66.0)

13.2

(7.3 to 20.8)

6

609.6

(381.9 to 866.3)

18.0

(11.4 to 25.5)

5

648.1

(373.1 to 989.5)

17.7

(10.2 to 26.7)

5

1662.3

(1005.2 to 2462.3)

18.2

(11.0 to 26.6)

5
Impaired kidney function

30.9

(20.7 to 43.0)

10.1

(7.0 to 13.3)

9

433.2

(290.1 to 582.4)

12.8

(8.7 to 17.2)

9

486.7

(328.1 to 658.2)

13.3

(9.0 to 17.7)

8

1220.8

(825.0 to 1631.3)

13.4

(9.1 to 17.7)

8
All risk factors

284.6

(243.5 to 330.1)

92.5

(90.0 to 94.7)

3187.4

(2890.3 to 3480.1)

94.2

(91.9 to 96.2)

3416.8

(3070.0 to 3713.7)

93.3

(90.4 to 95.8)

8542.4

(7811.7 to 9142.3)

93.5

(90.8 to 95.9)

DALYs
Environmental/occupational risks

3300.5

(2726.0 to 3891.1)

44.8

(41.2 to 48.9)

30721.3

(26771.0 to 34744.1)

38.7

(35.4 to 41.9)

20772.7

(17712.1 to 23952.4)

30.4

(27.2 to 33.8)

59385.1

(52184.3 to 66601.1)

32.6

(29.6 to 35.7)

Air pollution

2813.5

(2315.5 to 3335.0)

38.2

(34.8 to 42.4)

25012.2

(21855.3 to 28481.5)

31.5

(28.8 to 34.4)

15157.3

(12859.2 to 17550.5)

22.2

(19.6 to 24.7)

45354.4

(39644.7 to 51231.6)

24.9

(22.4 to 27.5)

Particulate matter pollution

2813.5

(2315.5 to 3335.0)

38.2

(34.8 to 42.4)

25012.2

(21855.3 to 28481.5)

31.5

(28.8 to 34.4)

15157.3

(12859.2 to 17550.5)

22.2

(19.6 to 24.7)

45354.4

(39644.7 to 51231.6)

24.9

(22.4 to 27.5)

Ambient particulate matter pollution

601.6

(342.4 to 947.2)

8.2

(4.7 to 12.6)

11

16464.4

(13034.7 to 19837.8)

20.7

(16.8 to 24.3)

6

12794.4

(10582.3 to 14939.8)

18.7

(15.9 to 21.3)

6

32174.3

(26024.8 to 37713.8)

17.7

(14.7 to 20.3)

7
Household air pollution from solid fuels

2211.9

(1672.1 to 2843.7)

30.0

(24.1 to 36.3)

3

8547.7

(5725.1 to 11894.2)

10.8

(7.4 to 14.6)

10

2362.9

(1208.0 to 4010.8)

3.5

(1.8 to 5.9)

21

13180.1

(9051.4 to 18251.8)

7.2

(5.0 to 9.9)

12
Suboptimal temperature

388.1

(218.2 to 523.4)

5.3

(3.0 to 6.9)

3990.4

1918.9 5495.2

5.0

(2.4 to 6.7)

4781.8

(3304.4 to 6505.7)

7.0

(4.8 to 9.4)

11147.2

(7627.1 to 14343.2)

6.1

(4.2 to 7.8)

High temperature

47.8

(−96.5 to 105.8)

0.6

(−1.2 to 1.5)

26

705.5

(−915.8 to 1714.1)

0.9

(−1.2 to 2.2)

26

157.2

(−86.5 to 330.0)

0.2

(−0.1 to 0.5)

26

974.0

(−1054.9 to 2209.6)

0.5

(−0.6 to 1.2)

26
Low temperature

341.9

(228.7 to 468.1)

4.6

(3.2 to 6.1)

18

3312.3

2105.0 4492.3

4.2

(2.6 to 5.6)

21

4635.8

(3120.5 to 6410.8)

6.8

(4.6 to 9.1)

11

10217.6

(7285.5 to 13306.5)

5.6

(4.1 to 7.2)

15
Other environmental risks

425.4

(261.0 to 619.3)

5.8

(3.6 to 8.1)

4701.7

2940.5 6647.4

5.9

(3.8 to 8.1)

2757.5

(1509.1 to4281.4)

4.0

(2.3 to 6.1)

8368.7

(4896.4 to 12449.2)

4.6

(2.7 to 6.7)

Lead exposure

425.4

(261.0 to 619.3)

5.8

(3.6 to 8.1)

16

4701.7

(2940.5 to6647.4)

5.9

(3.8 to 8.1)

16

2757.5

(1509.1 to 4281.4)

4.0

(2.3 to 6.1)

17

8368.7

(4896.4 to 12449.2)

4.6

(2.7 to 6.7)

18
Behavioral risks

4784.8

(3921.8 to 5724.2)

64.9

(57.7 to 71.1)

54996.6

(48292.3 to 61648.7)

69.2

(62.8 to 74.3)

47858.7

(42009.4 to 53511.3)

70.1

(64.0 to 75.5)

125894.2

(112086.3 to 139552.4)

69.2

(63.1 to 74.4)

Tobacco

1403.2

(1172.6 to 1668.1)

19.0

(17.7 to 20.5)

20564.6

(18373.1 to 22653.2)

25.9

(24.5 to 27.2)

21426.4

(19287.7 to 23852.1)

31.4

(29.9 to 33.0)

50725.1

(46709.8 to 54647.3)

27.9

(26.6 to 29.1)

Smoking

1148.2

(964.4 to 1374.8)

15.6

(14.5 to 16.8)

7

16962.1

(15179.7 to 18813.4)

21.4

(20.1 to 22.6)

5

18621.4

(16634.7 to 20751.6)

27.3

(25.7 to 28.8)

3

43452.8

(40296.9 to 46783.9)

23.9

(22.8 to 25.0)

3
Secondhand smoke

307.9

(231.0 to 392.7)

4.2

(3.3 to 5.1)

21

4491.7

(3573.1 to 5449.7)

5.7

(4.6 to 6.8)

17

3854.6

(3089.9 to 4686.1)

5.6

(4.6 to 6.7)

14

9566.1

(7720.3 to 11527.1)

5.3

(4.3 to 6.3)

16
Alcohol use

−136.9

(−243.4 to −32.4)

−1.9

(−3.2 to −0.5)

27

−698.2

(−1622.1 to 298.1)

−0.9

(−2.1 to 0.4)

27

−634.9

(−2086.6 to 792.4

−0.9

(−3.0 to 1.1)

27

−2002.9

(−5192.2 to 1210.8)

−1.1

(−2.9 to 0.7)

27
Dietary risks

4213.4

(3296.8 to 5165.6)

57.2

(48.1 to 65.1)

46290.8

(38413.0 to 53808.3)

58.3

(49.0 to 65.5)

38471.5

(31383.3 to 45528.6)

56.3

(46.9 to 64.5)

103864.0

(86829.0 to 120418.9)

57.1

(47.9 to 64.8)

Diet low in fruits

518.4

(208.4 to 792.6)

7.0

(2.9 to 10.2)

12

5923.0

(2616.3 to8617.0)

7.5

(3.3 to 10.7)

13

2717.2

(915.5 to 4311.2)

4.0

(1.4 to 6.2)

18

10233.4

(4241.4 to 15123.4)

5.6

(2.3 to 8.2)

14
Diet low in vegetables

720.9

(443.5 to 1002.4)

9.8

(6.2 to 13.3)

9

5119.0

(2810.4 to 7417.4)

6.4

(3.6 to 9.1)

15

1533.5

(789.5 to 2187.0)

2.2

(1.2 to 3.3)

24

8383.0

(4666.2 to 11970.2)

4.6

(2.5 to 6.5)

17
Diet low in legumes

975.6

(231.5 to 1654.5)

13.2

(3.2 to 21.3)

8

11339.7

(2493.7 to 18438.0)

14.3

(3.2 to 22.9)

8

8260.5

(1689.8 to 13358.6)

12.1

(2.5 to 19.5)

10

24309.0

(5263.1 to 39575.3)

13.4

(3.0 to 21.4)

8
Diet low in whole grains

1350.1

(513.8 to 1827.9)

18.4

(6.9 to 24.0)

5

13949.2

(5491.1 to 18410.2)

17.6

(6.9 to 22.9)

7

12342.6

(4516.7 to 16125.6)

18.1

(6.6 to 23.4)

7

32206.5

(12173.3 to 41835.0)

17.7

(6.6 to 23.0)

6
Diet low in nuts and seeds

431.7

(226.7 to 615.4)

5.9

(3.0 to 8.0)

15

6949.0

(3937.4 to 9314.8)

8.7

(5.0 to 11.6)

12

3753.1

(1692.1 to 5540.0)

5.5

(2.5 to 7.9)

15

12279.0

(6364.3 to 16919.1)

6.7

(3.5 to 9.2)

13
Diet high in processed meat

105.6

(16.3 to 300.2)

1.4

(0.2 to 3.9)

25

1226.6

(525.7 to 2397.6)

1.5

(0.7 to 3.0)

25

1336.9

(223.1 to 2883.4)

2.0

(0.3 to 4.2)

25

4141.9

(998.6 to 8024.1)

2.3

(0.6 to 4.4)

24
Diet high in sugar‐sweetened beverages

168.0

(127.3 to 216.6)

2.3

(1.8 to 2.7)

24

1503.0

(993.6 to 1975.7)

1.9

(1.2 to 2.4)

24

1555.2

(969.0 to 2053.0)

2.3

(1.5 to 2.9)

23

3973.2

(2470.2 to 5218.8)

2.2

(1.4 to 2.8)

25
Diet low in fiber

316.0

(128.3 to 529.4)

4.3

(1.7 to 7.2)

20

4429.8

(1985.5 to 7167.9)

5.6

(2.5 to 8.7)

18

2066.6

(794.0 to 3639.4)

3.0

(1.2 to 5.2)

22

7943.0

(3373.6 to 12978.3)

4.4

(1.8 to 7.0)

20
Diet low in seafood omega‐3 fatty acids

328.7

(105.9 to 472.3)

4.5

(1.4 to 6.0)

19

3517.8

(1291.9 to 4779.0)

4.4

(1.7 to 5.8)

20

2674.9

(1377.4 to 3509.5)

3.9

(2.0 to 4.9)

19

7409.7

(3373.5 to 9687.0)

4.1

(1.9 to 5.2)

23
Diet low in polyunsaturated fatty acids

396.0

(55.5 to 801.0)

5.4

(0.7 to 10.8)

17

4391.7

(494.1 to 8939.9)

5.5

(0.6 to 11.2)

19

2668.7

(327.0 to 5462.1)

3.9

(0.4 to 8.1)

20

8012.9

(969.2 to 16249.2)

4.4

(0.5 to 9.0)

19
Diet high in trans fatty acids

434.8

(62.8 to 681.0)

5.9

(0.8 to 8.9)

14

7026.9

(757.7 to 9634.3)

8.8

(1.0 to 11.8)

11

4442.8

(536.2 to 6299.3)

6.5

(0.8 to 9.0)

12

14234.2

(1580.4 to 19410.2)

7.8

(0.9 to 10.5)

11
Diet high in sodium

502.1

(56.5 to 1380.9)

6.8

(0.8 to 18.9)

13

5506.2

(664.7 to 13883.1)

6.9

(0.9 to 17.4)

14

9534.4

(3583.9 to 17346.5)

13.9

(5.4 to 25.3)

8

17353.9

(4712.3 to 36861.5)

9.5

(2.6 to 20.3)

10
Diet high in red meat

210.9

(16.0 to 431.0)

2.8

(0.2 to 5.5)

23

1811.2

(227.0 to 3476.8)

2.3

(0.3 to 4.3)

23

4041.5

(763.0 to 7352.2)

5.9

(1.1 to 10.7)

13

7742.3

(1340.0 to 14077.7)

4.3

(0.7 to 7.6)

21
Low physical activity

216.5

(67.2 to 553.9)

2.9

(0.9 to 7.1)

22

2834.7

(993.2 to 6465.1)

3.6

(1.2 to 7.9)

22

3044.1

(1062.3 to 6572.4)

4.5

(1.6 to 9.5)

16

7586.7

(2613.5 to 16747.2)

4.2

(1.4 to 9.1)

22
Metabolic risks

5904.1

(4880.7 to 6982.1)

80.1

(74.5 to 85.4)

66864.3

(59824.9 to 74118.4)

84.2

(79.2 to 88.9)

57478.9

(51676.0 to 63447.9)

84.2

(78.7 to 89.3)

153132.1

(138737.4 to 166795.4)

84.1

(78.9 to 89.1)

High systolic blood pressure

3913.3

(3136.6 to 4793.8)

53.1

(46.1 to 60.0)

1

43855.4

(37223.2 to 50863.4)

55.2

(47.7 to 62.2)

1

37876.8

31625.1 44054.7

55.5

(47.2 to 63.4)

1

99397.3

(84594.0 to 114599.3)

54.6

(46.8 to 61.9)

1
High LDL cholesterol

3167.6

(2445.5 to 3988.7)

43.0

(35.7 to 51.1)

2

36744.1

(29932.5 to 44167.9)

46.2

(38.6 to 54.3)

2

32561.5

(26484.5 to 39434.1)

47.7

(39.1 to 56.8)

2

84916.4

(69572.6 to 101382.5)

46.6

(38.5 to 55.0)

2
High fasting plasma glucose

1440.5

(914.6 to 2200.2)

19.6

(12.3 to 30.1)

4

19480.1

(12178.0 to 29165.7)

24.5

(15.4 to 36.9)

3

14266.4

(9167.9 to 21592.5)

20.9

(13.6 to 31.5)

5

43253.3

(27821.4 to 64164.6)

23.8

(15.3 to 35.8)

4
High body mass index

1212.4

(647.1 to 1923.3)

16.4

(9.2 to 25.1)

6

17398.3

(11114.2 to 24277.4)

21.9

(14.2 to 30.3)

4

15459.8

(9247.1 to 22706.6)

22.6

(13.6 to 32.9)

4

41369.8

(26027.7 to 58657.9)

22.7

(14.6 to 32.0)

5
Impaired kidney function

690.0

(467.3 to 943.4)

9.4

(6.7 to 12.2)

10

9646.1

(6657.7 to 12773.4)

12.1

(8.5 to 16.0)

9

8606.5

(5994.3 to 11537.3)

12.6

(8.9 to 16.4)

9

22516.9

(15811.0 to 29665.1)

12.4

(8.8 to 16.1)

9
All risk factors

6851.9

(5826.9 to 7984.3)

93.0

(91.1 to 94.7)

75243.9

(68129.9 to 82384.2)

94.7

(93.1 to 96.1)

64607.6

(58844.1 to 70173.0)

94.6

(92.6 to 96.3)

172100.0

(160171.2 to 184131.0)

94.5

(92.7 to 96.2)

DALYs indicates disability‐adjusted life years; IHD, ischemic heart disease; LDL, low‐density lipoprotein; and PAF, population‐attributable fraction. Deaths‐ and DALY‐based PAFs were ranked for 27 individual risk factors at level 4.

The number ranges in parentheses refers to 95% uncertainty intervals of corresponding numbers. *UI: uncertainty interval.