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. 2021 Aug 25;10(17):e021674. doi: 10.1161/JAHA.121.021674

Table 1.

Baseline Demographics and Characteristics of the 2 Study Groups

Variable

Overall

(N=7860)

Post‐DCCV anticoagulation

(N=5510)

No Post‐DCCV anticoagulation

(N=2350)

P Value
Age, y 74.2±8.6 74.8±7.9 72.9±10 <0.001
Male sex 4488 (57.1) 3242 (58.8) 1246 (53.0) <0.001
White race 7123 (90.6) 5077 (92.1) 2046 (87.1) <0.001
Black race 275 (3.5) 140 (2.5) 135 (5.7)
Asian race 94 (1.2) 58 (1.1) 36 (1.5)
Hispanic ethnicity 115 (2.6) 115 (2.1) 87 (3.7)
Diabetes mellitus 2639 (33.6) 1859 (33.7) 780 (33.2) 0.6
Hypertension 6702 (85.3) 4869 (88.4) 1833 (78.0) <0.001
History of heart failure 2593 (33.0) 2057 (37.2) 536 (22.8) <0.001
Prior coronary artery disease 3497 (44.5) 2647 (48.0) 850 (36.2) <0.001
Prior bleeding 1384 (17.6) 1013 (18.4) 371 (15.8) 0.006
Prior gastrointestinal bleed 602 (7.7) 431 (7.8) 171 (7.3) 0.4
Prior cerebral bleed 50 (0.6) 32 (0.6) 18 (0.8) 0.3
Prior ischemic stroke 1125 (14.3) 833 (15.1) 292 (12.4) 0.002
Prior smoking 1049 (13.4) 753 (13.7) 296 (12.6) 0.2
Peripheral artery disease 1832 (23.3) 1335 (24.2) 497 (21.2) 0.003
Liver disease 403 (5.1) 287 (5.2) 116 (4.9) 0.6
Chronic kidney disease 1078 (13.7) 815 (14.8) 263 (11.2) <0.001
End‐stage renal disease 108 (1.4) 71 (1.3) 37 (1.6) 0.3
Prior permanent pacemaker 826 (10.5) 647 (11.7) 179 (7.6) <0.001
Prior intracardiac defibrillator 425 (5.4) 341 (6.2) 84 (3.6) <0.001
Valvular heart disease 3300 (42.0) 2569 (46.6) 731 (31.1) <0.001
Sleep apnea 1681 (21.4) 1295 (23.5) 386 (16.4) <0.001
Dementia 319 (4.1) 196 (3.6) 123 (5.2) 0.001
Obesity 2046 (26.0) 1529 (27.8) 517 (22.0) <0.001
Hypothyroid 1982 (25.2) 1417 (25.7) 565 (24.0) 0.1
Anemia 1981 (25.2) 1442 (26.2) 539 (22.9) 0.003
Metastatic tumor 154 (2.0) 104 (1.9) 50 (2.1) 0.5
Rheumatoid arthritis/connective tissue disease 603 (7.7) 419 (7.6) 184 (7.8) 0.7
Lung disease 2260 (28.8) 1633 (29.6) 627 (26.7) 0.008
Depression 1027 (13.1) 704 (12.8) 323 (13.7) 0.2
Alcohol abuse 181 (2.4) 134 (2.4) 47 (2.0) 0.2
Frailty score 2.9 (0–8.2) 3.0 (0–8.5) 2.4 (0–7.4) <0.001
Atrial flutter 849 (10.8) 563 (10.2) 286 (12.2) 0.01
Precardioversion TEE 3066 (39.0) 2458 (44.6) 608 (25.9) <0.001
Precardioversion anticoagulation for at least 3‐4 weeks 5299 (67.4) 4876 (88.5) 423 (18.0) <0.001
Warfarin 1647 (21.0) 1484 (26.9) 163 (6.9)
Apixaban 2005 (25.5) 1867 (33.9) 138 (5.9)
Rivaroxaban 1454 (18.5) 1344 (24.4) 110 (4.7)
Dabigatran 410 (5.2) 387 (7.0) 23 (1.0)
CHA2DS2‐VASc score 4.1±1.7 4.2±1.7 3.7±1.7
1 403 (5.2) 200 (3.6) 203 (8.7) <0.001
2 1046 (13.3) 631 (11.5) 415 (17.7)
3 1599 (20.3) 1112 (20.2) 487 (20.7)
4 1881 (23.9) 1349 (24.5) 532 (22.6)
5 1438 (18.3) 1072 (19.5) 366 (15.6)
6 836 (10.6) 634 (11.5) 202 (8.6)
≥7 657 (8.4) 512 (9.3) 145 (6.2)
Rural practice zip code 802 (10.4) 508 (9.2) 294 (12.5) <0.001
Post‐DCCV anticoagulation
Warfarin 1470 (26.7) NA NA
Apixaban 2165 (39.3) NA
Rivaroxaban 1472 (26.7) NA
Dabigatran 403 (7.3) NA

Results are presented as n (%) and mean±standard deviation.

DCCV indicates direct‐current cardioversion; NA, not applicable; and TEE, transesophageal echocardiography.