Table 3.
Multivariable Analyses of the Relationship Between the Presence of an Anxiety Disorder and Macrovascular, Microvascular, and Any CED Across All Patients and in Men and Women After Stratifying by Sex
| Odds ratio (95% CI) | Abnormal %ΔCADAch | P Value | Abnormal %ΔCBFAch | P Value | Any CED | P Value |
|---|---|---|---|---|---|---|
| All patients | ||||||
| No anxiety disorder (reference) |
N=427 1.00 |
N=712 1.00 |
N=790 1.00 |
|||
| Anxiety disorder |
N=165 1.01 (0.81–1.26) |
0.907 |
N=312 1.37 (1.11–1.68) |
0.003* |
N=343 1.36 (1.10–1.68) |
0.004* |
| Men | ||||||
| No anxiety disorder (reference) |
N=331 1.00 |
N=463 1.00 |
N=504 1.00 |
|||
| Anxiety disorder |
N=126 0.99 (0.69–1.43) |
0.966 |
N=206 1.28 (0.89–1.84) |
0.180 |
N=221 1.31 (0.90–1.89) |
0.155 |
| Women | ||||||
| No anxiety disorder (reference) |
N=129 1.00 |
N=249 1.00 |
N=286 1.00 |
|||
| Anxiety disorder |
N=51 1.01 (0.76–1.34) |
0.946 |
N=106 1.44 (1.12–1.86) |
0.005* |
N=122 1.40 (1.08–1.81) |
0.010* |
Multivariable analysis was adjusted for age and body mass index as continuous variables, and White race, hypertension, diabetes, hyperlipidemia, smoking, and use of psychotropic drugs as categorical variables. %ΔCADAch indicates percentage change in coronary artery diameter in response to acetylcholine; %ΔCBFAch, percentage change in coronary blood flow in response to acetylcholine; and CED, coronary endothelial dysfunction.
P value <0.05.