Skip to main content
. 2021 Sep 2;10(17):e020895. doi: 10.1161/JAHA.121.020895

Figure 7. Schematic showing the mechanistic role of the Hif‐1α‐p53 axis in cardiac rupture after myocardial infarction (MI).

Figure 7

Hif‐1α indicates hypoxia‐inducible factor 1‐α; Hif‐1β, hypoxia‐inducible factor 1‐β; IL‐1β, interleukin‐1β; MMP/TIMP, matrix metalloproteinase/tissue inhibitor of metalloproteinase; OH, hydroxy group; and PHD, prolyl hydroxylase domain‐containing protein.