Table 1.
General characteristic data of the study population
| Variables | No AF (n = 63) |
AF (n = 16) |
P value |
|---|---|---|---|
| Age (years) | 65 [59–70] | 73 [65–76] | 0.026 |
| BMI (kg.m−2) | 31.5 [24.9–40.7] | 29.3 [26.2–32.8] | 0.8 |
| SAPS II score during TTE | 32 [21–49] | 58 [43–62] | 0.001 |
| Male gender (n; %) | 40 (65) | 14 (88) | 0.12 |
| Medical history | |||
| No history | 8 (13) | 3 (19) | 0.68 |
| Hypertension | 31 (50) | 12 (75) | 0.09 |
| Diabetes | 13 (21) | 6 (38) | 0.19 |
| Dyslipidemia | 19 (31) | 4 (25) | 0.76 |
| Smoking (former or active) | 20 (33) | 4 (25) | 0.76 |
| Chronic renal disease | 5 (8) | 2 (12) | 0.62 |
| COPD/asthma | 11 (18) | 2 (13) | 1 |
| Coronary or peripheral artery disease | 15 (24) | 5 (32) | 0.53 |
| Obstructive sleep apnea | 5 (8) | 1 (6) | 1 |
| Chronic treatment | |||
| Statine | 19 (31) | 7 (44) | 0.38 |
| Beta blocker | 17 (28) | 6 (38) | 0.54 |
| ACE inhibitor | 11 (18) | 5 (32) | 0.30 |
| ARBs | 14 (23) | 3 (18) | 1 |
| Diuretic | 9 (15) | 4 (25) | 0.45 |
| Aspirin | 14 (23) | 6 (38) | 0.33 |
| Metformin | 9 (15) | 4 (25) | 0.45 |
| Time to first symptom to ICU admission (days) | 8 [5–11] | 8 [4–14] | 0.56 |
| COVID 19 specific treatment (n = 67/89) | |||
| Dexamethasone | 49 (81) | 11 (74) | 0.70 |
| Remdesevir | 3 (5) | 0 | 1 |
| Tocillizumab | 1 (2) | 0 | 1 |
| Atrial fibrillation | |||
| Previous paroxysmal AF | 6 (10) | 2 (12) | 0.61 |
| Occurrence of AF, (days) | – | 7 [2–11] | – |
| CHA2DS2-VASc | 2 [1–3] | 3 [1–4] | 0.20 |
| Outcome | |||
| Arterial thromboembolic events | 0 | 1 (6)* | 0.21 |
| Length under MV, days | 17 [10–24] | 28 [16–44] | < 0.001 |
| Mortality at 30-days | 14 (22) | 7 (43) | 0.11 |
| ICU discharge, days | 61 (93) | 13 (82) | 0.06 |
| Length of stay in ICU, days | 12 [5–21] | 25 [14–33] | < 0.001 |
Bold indicates P < 0.05
Continuous variables are expressed as median [interquartile range] and categorical variables as number (percentage)
ACE angiotensin-converting enzyme, AF atrial fibrillation, ARBs angiotensin II receptor blockers, BMI body mass index, COPD chronic obstructive pulmonary disease, ICU intensive care unit, MV mechanical ventilation, SAP systolic arterial pressure, SAPS simplified acute physiology score, TTE transthoracic echocardiography
*ischemic stroke