Figure 5.

Structure of phthalate and terephthalate bound PDO_KF1complexes to reveal the protein interactions that are important for correctly positioning substrate.A, electron density omit maps (contoured at 3σ) at 2.7 Å, 3.1 Å resolution for phthalate and terephthalate, respectively in the active site. B, the coordination state of the mononuclear iron in presence of phthalate and terephthalate. C, the phthalate molecule is anchored in the active site of PDO_KF1via interactions that are highlighted here. D, similarly, the terephthalate molecule is anchored in the active site of PDO_KF1via interactions that are highlighted here. The interactions are represented with black dotted lines. Residues and bond distances (in Å) are labeled.