Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 26;20:15330338211060202. doi: 10.1177/15330338211060202

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 1. — Venn diagram, protein-protein interaction (PPI) network, the most significant module, and the top 10 highest scoring nodes of differentially expressed genes (DEGs). (A) DEG identification in three gene expression profile datasets (GSE18842, GSE44077, and GSE19804). In total, 594 DEGs were identified. (B) A PPI network was generated using Cytoscape (combined score ≥ 0.9). (C) The significant module obtained from the PPI network contained 24 nodes and 256 edges. (D) The interaction network of the 10 nodes with the highest screening scores. Upregulated genes are marked in dark red; downregulated genes are marked in dark blue. The red, orange, and yellow nodes represented the top 10 hub genes in the network.