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. 2021 Sep 3;30(11):2459–2470. doi: 10.1177/09622802211037073

Table 3.

Selected main trial sample sizes (clusters per arm) accounting for the uncertainty in the ICC, for a range of cluster sizes, ICCs and pilot clusters per arm, calculated using result (6). Cluster size is assumed to be equal in pilot and main trials. Effect size d  =  0.25.

ICC Clusters per arm Swiger's method Searle's method Fisher's transformation
Cluster size Cluster size Cluster size
5 10 15 20 30 5 10 15 20 30 5 10 15 20 30
0.01 4 82 43 30 23 17 90 50 35 28 20 85 45 32 25 18
8 78 41 28 22 16 82 44 31 24 17 80 42 29 23 16
10 77 40 28 22 16 80 42 30 23 17 78 41 29 22 16
15 76 40 27 21 15 77 41 28 22 16 77 40 28 22 16
20 75 39 27 21 15 76 40 28 22 16 75 39 27 21 15
0.05 4 90 53 41 35 29 99 62 49 42 36 92 56 43 37 31
8 86 51 39 34 28 90 55 43 37 31 87 52 41 35 29
10 85 50 39 34 28 88 54 42 36 31 86 52 40 35 29
15 84 50 39 33 28 86 52 41 35 30 84 51 40 34 29
20 83 50 39 33 28 85 51 40 35 29 84 50 39 34 29
0.10 4 101 67 56 50 45 110 77 66 61 55 103 70 59 54 48
8 97 65 55 50 44 102 70 60 54 49 99 67 57 51 46
10 97 65 55 49 44 100 69 59 53 48 98 66 56 51 46
15 96 65 54 49 44 98 67 57 52 47 97 66 56 50 45
20 95 65 54 49 44 97 67 56 51 46 96 65 55 50 45
0.20 4 125 96 86 82 77 135 108 99 95 90 126 99 90 86 81
8 122 95 86 81 77 128 101 92 88 83 124 97 88 84 79
10 122 95 86 81 77 127 100 91 86 82 123 97 88 83 79
15 122 95 86 81 77 125 98 89 85 80 123 96 87 83 78
20 122 95 86 81 77 124 97 88 84 79 123 96 87 82 78

ICC: intra-cluster correlation.