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. 2021 Nov 26;20(1):15593258211057768. doi: 10.1177/15593258211057768

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© The Author(s) 2022

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — The experimental time schedule (A) and the effect of Lycium barbarum berry extract on the body weight of radiation exposed BALB/c mice (B). The body weight of the mice in the sham exposure group (Sham) increases steadily, but it decreases significantly after acute X-ray irradiation with 5.5 Gy in the experimental control (Exp-Ctrl), mice treated with Lycium barbarum berries (Exp-Lyc) and amifostine (Ami-Exp) at 1 week after the exposure (F (3, 36) = 61.85, P < .0001). From the second week, amifostine pretreatment (Ami- Exp) and oral Lycium barbarum berry extract treatment after exposure (Exp-Lyc) reverse the animal weight loss (F (3, 36) = 134.0, P < .0001) and these animals have similar body weight to Sham group at the end of the fifth week (F (3, 36) = 244.0, P < .0001). However, Exp-Ctrl group has a significant weight loss from 2 to 5 week(s) after radiation exposure when compared to the other 3 groups (P < .05, n = 10 in each group).