Table 2.
Annual Changes in Lipids (mg/dL) Within Each Time Segment in Relationship to the FMP Adjusted for Study Site and Ethnicity and Their Comparison Within Participant From Piece‐Wise Mixed Effect Models With Random Intercept (n=1554 Women)
| Lipid |
A. >3 y Before FMP Beta (SE) |
P Value |
B. 3 y before FMP to 1 y after FMP Beta (SE) |
P Value |
C. 1–3 y Post FMP Beta (SE) |
P Value |
D. >3 y Post FMP Beta (SE) |
P Value |
A vs B P Value |
B vs C P Value |
C vs D P Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total cholesterol | 0.375 (0.167) | 0.025 | 4.644 (0.240) | <.0001 | −1.438 (0.469) | 0.002 | −0.650 (0.106) | <.0001 | <.0001 | <.0001 | 0.127 |
| LDL‐C | −0.221 (0.156) | 0.157 | 3.166 (0.209) | <.0001 | −1.455 (0.403) | <.001 | −0.825 (0.084) | <.0001 | <.0001 | <.0001 | 0.153 |
| ApoB | −0.192 (0.134) | 0.154 | 2.923 (0.188) | <.0001 | 1.854 (0.381) | <.0001 | 0.401 (0.082) | <.0001 | <.0001 | 0.034 | <.001 |
|
A. up to FMP Beta (SE) |
P Value |
B. FMP to 3 y Post‐FMP Beta (SE) |
P Value |
C. >3 y Post‐FMP Beta (SE) |
P Value |
A vs B P Value |
B vs C P Value |
|
|---|---|---|---|---|---|---|---|---|
| Log triglycerides | 0.015 (0.002) | <.0001 | 0.014 (0.003) | <.0001 | −0.009 (0.001) | <.0001 | 0.7148 | <.0001 |
| Apo A1 | 2.504 (0.092) | <.0001 | 0.287 (0.232) | 0.215 | −0.710 (0.077) | <.0001 | <.0001 | <.001 |
| HDL‐C | 0.488 (0.018) | <.0001 |
Bold text indicates p values that are less than .05.
FMP indicates final menstrual period; HDL‐C, high‐density lipoprotein cholesterol; and LDL‐C, low‐density lipoprotein cholesterol.