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. 2021 Sep 6;10(18):e021362. doi: 10.1161/JAHA.121.021362

Table 4.

Beta Coefficients of the Interaction between Age at Final Menstrual Period and Woman‐Specific Slopes for Lipids in the Segment from 1 to 3 y Post‐FMP Predicting Subclinical Carotid Measures at Visits 12/13

Age At FMP By Early Postmenopause Woman‐Specific Slope Total Cholesterol LDL‐Cholesterol Apolipoprotein B
β (SE) P Value β (SE) P Value β (SE) P Value
Intima media thickness, mm
Model 0 0.00074 (0.00022) <.001 0.00074 (0.00024) 0.002 0.00092 (0.00028) 0.001
Model 1 0.00063 (0.00021) 0.002 0.00054 (0.00023) 0.018 0.00056 (0.00027) 0.042
Model 2 0.00065 (0.00021) 0.002 0.00056 (0.00023) 0.015 0.00058 (0.00028) 0.036
Adventitial diameter, mm
Model 0 0.00408 (0.00121) <.001 0.00514 (0.00158) 0.001 0.00514 (0.00158) 0.001
Model 1 0.00339 (0.00112) 0.003 0.00350 (0.00148) 0.018 0.00350 (0.00148) 0.018
Model 2 0.00328 (0.001) 0.004 0.00337 (0.00124) 0.007 0.00349 (0.00148) 0.018
Carotid plaque (≥2)
Model 0 0.00863 (0.00429) 0.044 0.00857 (0.00470) 0.068 0.00890 (0.00564) 0.115
Model 1 0.01110 (0.00458) 0.016 0.01160 (0.00499) 0.020 0.00860 (0.00588) 0.143
Model 2 0.01170 (0.00466) 0.021 0.01250 (0.00509) 0.023 0.00965 (0.0059) 0.105

Model 0: Adjusted for age at FMP and subject‐specific slope for lipid changes during the segment 1–3 y post‐FMP.

Model 1: Model 0 adjusted with V12 age, systolic blood pressure, body mass index, use of blood pressure medication, use of diabetes mellitus medication, and ever stroke/heart attack before V12.

Model 2: Model 1 adjusted with ever smoker and anti‐lipid medications at V12/13.

FMP indicates final menstrual period; and LDL, low‐density lipoprotein.

Bold text indicates p values that are less than .05.