Table 4.
Age At FMP By Early Postmenopause Woman‐Specific Slope | Total Cholesterol | LDL‐Cholesterol | Apolipoprotein B | |||
---|---|---|---|---|---|---|
β (SE) | P Value | β (SE) | P Value | β (SE) | P Value | |
Intima media thickness, mm | ||||||
Model 0 | 0.00074 (0.00022) | <.001 | 0.00074 (0.00024) | 0.002 | 0.00092 (0.00028) | 0.001 |
Model 1 | 0.00063 (0.00021) | 0.002 | 0.00054 (0.00023) | 0.018 | 0.00056 (0.00027) | 0.042 |
Model 2 | 0.00065 (0.00021) | 0.002 | 0.00056 (0.00023) | 0.015 | 0.00058 (0.00028) | 0.036 |
Adventitial diameter, mm | ||||||
Model 0 | 0.00408 (0.00121) | <.001 | 0.00514 (0.00158) | 0.001 | 0.00514 (0.00158) | 0.001 |
Model 1 | 0.00339 (0.00112) | 0.003 | 0.00350 (0.00148) | 0.018 | 0.00350 (0.00148) | 0.018 |
Model 2 | 0.00328 (0.001) | 0.004 | 0.00337 (0.00124) | 0.007 | 0.00349 (0.00148) | 0.018 |
Carotid plaque (≥2) | ||||||
Model 0 | 0.00863 (0.00429) | 0.044 | 0.00857 (0.00470) | 0.068 | 0.00890 (0.00564) | 0.115 |
Model 1 | 0.01110 (0.00458) | 0.016 | 0.01160 (0.00499) | 0.020 | 0.00860 (0.00588) | 0.143 |
Model 2 | 0.01170 (0.00466) | 0.021 | 0.01250 (0.00509) | 0.023 | 0.00965 (0.0059) | 0.105 |
Model 0: Adjusted for age at FMP and subject‐specific slope for lipid changes during the segment 1–3 y post‐FMP.
Model 1: Model 0 adjusted with V12 age, systolic blood pressure, body mass index, use of blood pressure medication, use of diabetes mellitus medication, and ever stroke/heart attack before V12.
Model 2: Model 1 adjusted with ever smoker and anti‐lipid medications at V12/13.
FMP indicates final menstrual period; and LDL, low‐density lipoprotein.
Bold text indicates p values that are less than .05.