Table 1.
Change in Body Weight, Heart Weight, and Blood Glucose Levels
| Item | Unit | WT Ctrl. (n=5) | WT DM (n=6) | ALDH2*2 Ctrl. (n=6) | ALDH2*2 DM (n=6) |
|---|---|---|---|---|---|
| BW | g | 31.92±2.10 | 23.52±2.24* | 32.08±2.05 † | 22.20±1.68* , ‡ |
| HW | g | 0.14±0.01 | 0.13±0.01 | 0.14±0.01 | 0.14±0.02 |
| HW/BW | % | 0.45±0.01 | 0.54±0.07* | 0.44±0.02 † | 0.59±0.09* , ‡ |
| HW to tibia length | mg/mm | 6.37±0.37 | 5.58±0.35* | 6.35±0.68 † | 6.07±0.66 |
| Blood glucose | mg/dL | 168.00±22.00 | 411.67±107.81* | 167.00±31.62 † | 401.67±105.55* , ‡ |
ALDH2*2 indicates aldehyde dehydrogenase 2 mutant allele; BW, body weight; Ctrl., control; DM, diabetes mellitus; HW, heart weight; HW/BW, heart weight to body weight ratio; HW/TL, heart weight to tibia length; and WT, wild type.
*
P<0.05 vs WT Ctrl.
†
P<0.05 vs WT DM.
‡
P<0.05 vs ALDH2*2 Ctrl.