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. 2021 Nov;10(11):2921–2928. doi: 10.21037/tp-21-283

Table 2. Patient characteristics and outcome according to the etiology.

Variables All patients (n=74) Immune related (n=7) Liver dysfunction (n=4) Cardiovascular causes (n=3) Miscellaneous (infection and other conditions) (n=12) IPH (n=48) P value
Age, year 3.5 (1.5–7) 9 (6.0–11.0) 0.15 (0.1–0.425) 13 (0.6–13) 1.5 (0.7–5.5) 4.0 (2–6.8) 0.001
Male gender, % 38 (51.4) 4 (57.1) 4 (100.0) 3 (100.0) 4 (33.3) 23 (47.9) 0.078
Course, month 1 (0.3–12.3) 1 (1–6) 0.7 (0.325–4.75) 0.1 (0.075–0.55) 0.25 (0.1–3) 4.0 (1.0–16) 0.006
Presenting symptoms
   Fever 29 (39.2) 2 (28.6) 2 (50.0) 1 (33.3) 8 (66.7) 16 (33.3) 0.288
   Cough 45 (60.8) 3 (42.9) 0 (0) 1 (33.3) 3 (25.0) 38 (79.2) <0.001
   Anemia 62 (83.8) 7 (100.0) 3 (75.0) 0 (0) 7 (58.3) 45 (93.8) <0.001
   Hemoptysis 48 (64.9) 4 (57.1) 1 (25.0) 3 (100.0) 9 (75) 31 (64.6) 0.280
   Dyspnea 33 (44.6) 3 (42.9) 3 (75.0) 3 (100.0) 11 (91.7) 12 (25.0) <0.001
   Hypoxia 32 (43.2) 4 (57.1) 4 (100.0) 2 (66.7) 11 (91.7) 11 (22.9) <0.001
   Clubbing 2 (2.7) 0 (0) 0 (0) 1 (33.3) 0 (0) 1 (2.1) 0.024
   Crackles 20 (27.0) 0 (0) 0 (0) 1 (33.3) 6 (50.0) 13 (27.1) 0.123
Hb, g/L 76.8±32 67.3±22.6 82.8±15.2 159±64.9 94.4±30.1 68.1±22.6 0.002
Pulmonary infiltrates 66 (89.2) 7 (100.0) 3 (75.0) 3 (100.0) 9 (75.0) 44 (91.7) 0.309
DAH classical triad* 36 (48.6) 4 (57.1) 1 (25.0) 0 (0) 4 (33.3) 27 (56.3) 0.192

*, refers to hemoptysis, anemia and pulmonary infiltrates on chest imaging.