Table 2.

Multivariable Cox regression models predicting overall mortality in de novo metastatic prostate cancer patients according to chemotherapy status prior to and after propensity score matching.

	Variable of interest	Univariable			Multivariable
		Hazard Ratio	95%-CI	p-value	Hazard Ratio	95%-CI	p-value
Unmatched data	chemotherapy-exposed vs. naïve	0.73	0.63-0.83	<0.001	0.82	0.72-0.96	0.01
After propensity score matching	chemotherapy-exposed vs. naïve	0.77	0.66-0.90	0.001	0.77	0.66-0.90	<0.001

Cox regression models were adjusted for age, PSA, Gleason Group Grade, cT-stage, cN-stage, cM-stage and local treatment.