Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 23;12:785463. doi: 10.3389/fimmu.2021.785463

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Wang, Yi, Liu, Tan, Jin, Li, Zhou, Wang and Kang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

HOTAIR regulated gene expression participated in multiple biological processes in different dataset. (A) HOTAIR upregulated 2201 genes after 6h expressing in U87 and 4975 genes after 48h, respectively, and there were 1920 overlapping genes. (B) HOTAIR downregulated 579 genes and 1827 genes when HOTAIR were expressed for 6h and 48h in U87 respectively, and the overlapping genes reached 470. (C, D) HOTAIR regulated genes were enriched in several biological processes (C) and pathways (D). (E) HOTAIR expression in CGGA RNAseq dataset (n=301). (F) Cluster heatmap showed the gene expression level correlated with HOTAIR expression in glioma based on CGGA RNAseq dataset (n=301). (G) Quantifiable genes of GBM patients in CGGA RNAseq dataset associated with HOTAIR were classified by ontology annotation based on biological processes.