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. 2021 Nov 23;23(1):68. doi: 10.3892/etm.2021.10991

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Copyright: © Tang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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SchB improves THP-induced body weight, food intake and echocardiographic changes in rats. (A) Body weights and (B) food intake of THP-treated rats decreased in the third and fourth weeks. (C) EF and (D) %FS decreased, and (E) LVIDd and (F) LVIDs increased in THP-treated rats. After treatment with SchB, the aforementioned changes were effectively alleviated. All values are presented as the mean ± SD. ^*P<0.05 vs. CON; ^#P<0.05 vs. THP. EF, left ventricular ejection fraction; FS, left ventricular shortening fraction; LVIDd, left ventricular internal diameter at end-diastole; LVIDs, left ventricular internal diameter at end-systole; CON, control; SchB, schisandrin B; THP, pirarubicin.