Figure EV2. Histology of the heart (haematoxylin and eosin staining and electron microscopy).

1. Representative photomicrographs of heart tissue, stained with haematoxylin and eosin, from wild‐type (WT, upper panel) and Uqcrh ^−/− (lower panel) mice at 9 weeks of age. Normal histopathological structure of the myocardium (red box, central panels) and aorta (black box, right panels) were observed in both groups of mice. Scale bars represent 1 mm in the left panels and 50 μm in the central and right panels.
2. Electron microscopy images of 3 representative wild‐type (WT, upper panel) and 3 Uqcrh ^−/− mice (lower panel) heart mitochondria. Mitochondria from Uqcrh^−/− mouse heart tissue showed paracrystalline inclusions (arrows). Magnification 1:50,000.