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. 2021 Nov 23;8:782231. doi: 10.3389/fmed.2021.782231

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Copyright © 2021 Liu, Yang, Liu, Lei, Wang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A 58-year-old man was diagnosed with peritoneal metastasis due to post-operative re-examination of pancreatic cancer. After receiving Carrelizumab immunosuppressive therapy, ⁶⁸Ga-FAPI PET/CT was performed [(A): after 1 cycle; (B): after 4 cycles]. After the first cycle, the thyroid showed diffuse increased FAPI uptake with SUVmax of 6.1, and TBR 7.46; blood analysis showed FT3 2.86, FT4 1.18, TSH 13.193, TgAb 12.06, and TPOAb <0.05; after the fourth cycle, the thyroid also showed diffuse increased FAPI uptake with SUVmax of 3.9, and TBR 6.26; blood analysis showed FT3 2.49, FT4 1.02, TSH 7.096, TgAb <0.12, and TPOAb <0.05; Finally, a diagnosis of immune-related thyroiditis was made.