Figure 7.

Reduced cardiac inflammation after treatment with Telmisartan and correlation analysis of cardiac inflammation and fibrosis. (a) Cardiac H&E staining and (b) CD68 immunohistochemical staining at week 16 and (c) the calculated mean ± SD of percentage of cardiac macrophages at week 16. (d) Cardiac inflammatory cells (H&E, left), macrophages (CD68, middle), and fibrosis (Masson, right) in adjacent cardiac slices and (e) the quantitative correlation analysis between percentage of macrophages area and percentage of fibrosis area (R² = 0.68; P < 0.001). Scale bar in (b) and (d), 100 μm. H&E indicates hematoxylin & eosin; Masson: Masson trichrome. (A color version of this figure is available in the online journal.)